Marijuana

Question 1

medical use of marijuana dates back to

Answer 1

ancient times

Question 2

cannabis sativa

Answer 2

2 varieties of plant

• a psychoactive
• non-psychoactive

Question 3

psycoactive cannabis

Answer 3

slow growing
weaker fabric
high cannabinoid content
—-delta-9-tetrahydrocannabinol & at lease 66 other cannabinoids

Question 4

non-psychoactive cannabis

Answer 4

Hemp

• easy and fast growing
• stronger plant fiber
• contains cannabinoids, but little THC
• many industrial uses (ropes, clothing, oils)

Question 5

Cannabis Sative L.

Answer 5

2 subspecies:
Cannabis sativa
Cannabis indica

Question 6

cannabis sativa

Answer 6

higher THC content

-more euphoria

Question 7

cannabis indica

Answer 7

higher content of cannabidol (CBD)

-more medicinal applications (sleep aid, relaxation)

Question 8

myrcene

Answer 8

anxiety and insomnia

Question 9

Most commonly used illegal drug

Answer 9

marijuana

Question 10

marijuana is legal for recreational use in

Answer 10

Canada

Question 11

marijuana is associates with

Answer 11

cigarette and alcohol use

Question 12

1 cash crop in America

Answer 12

marijuana

Question 13

Cannabis sativa, psychoactive forms:

Answer 13

marijuana, bhang, ganja, hashish, hash oil, dab

Question 14

marijuana

Answer 14

dried leaves and flowers

• usually smoked; can be baked in foods
• wide range of THC contents (5-15% THC)
• sinsemilla: without seeds (25-35% THC)

Question 15

Bhang

Answer 15

entire of plant after top has been picked

• ground into powder
• often mixed into drinks

Question 16

Ganja

Answer 16

made of the tops of female plants

-resin is still present

Question 17

Hashish

Answer 17

resin from top of female plant

-dried & then smoked or baked in food

Question 18

Hash oil

Answer 18

solvents are used to extract the cannabinoids

-tend to have high THC content (15-70%)

Question 19

Dab

Answer 19

concentrated hash oil

• infuse marijuana with butane gas
• 80-90% pure THC

Question 20

Absorption in marijuana

Answer 20

high lipid soluble, readily dissolve in water

• oral
• inhalation

Question 21

oral marijuana

Answer 21

slow

Question 22

inhalation of marijuana

Answer 22

10-25% of cannabinoids are absorbed

• depth of inhalation is more important than length
• average 15 min to reach blood stream

Question 23

Distribution of marijuana

Answer 23

only 1% enters the brain

-distributed all over body

Question 24

Where does marijuana work in the brain?

Answer 24

2 cannabinoid receptors

• CB1
• CB2
• *they both work to influence GABA, endorphins, and dopamine

Question 25

CB1

Answer 25

found primarily in brain

Question 26

CB2

Answer 26

found primarily in periphery | -immune system

Question 27

endogenous agents

Answer 27

endocannabinoids - Anadamide - 2AG

Question 28

2AG

Answer 28

more abundant in brain, its the primary one

Question 29

Why not develop CB1 and CB2 (ant)agonist?

Answer 29

there has been a development of various CB1 & CB2 agonist and antagonist -they seem to be less effective than the effects observed from cannabis

Question 30

Efficacy of Cannabis

Answer 30

Pharmacodynamic interaction of THC & CBD - THC psychoactive efficient can be blunted in CBD - medicinal effect may be enhanced by CBD

Question 31

Excretion of marijuana

Answer 31

most metabolite take place in liver | -converted to metabolites that rapidly cross into the brain

Question 32

how long does it take for marijuana to remove 1/2 dose?

Answer 32

20-30 hours

Question 33

how long can marijuana be detected in body?

Answer 33

30 days

Question 34

effects of ∆9 THC

Answer 34

psychological, perceptual, physical

Question 35

psychological effect of ∆9 THC

Answer 35

euphoria, relaxation, sleepiness, "insight"

Question 36

perceptual effects of ∆9 THC

Answer 36

altered perception of space and time, mood change, introspectin, more creative

Question 37

physical effects of ∆9 THC

Answer 37

increased heart rate, reddening of eyes, increased appetite, decreased coordination, dry mouth, possible headache

Question 38

long term affects of marijuana

Answer 38

fairly minimal to date

Question 39

long term affects in adolescents of marijuana (10-15 years old)

Answer 39

significant relationship between early heavy use and the development of psychotic disorders in adulthood -regular marijuana use may alter adolescent brain development

Question 40

Marijuana comes from which plant?

Answer 40

Cannabis sativa

Question 41

What seems to be the opinion of physicians about the medical usefulness of marijuana?

Answer 41

-It is not very useful and its use may cause other medical problems. -More research regarding its medical usefulness is needed.

Question 42

There is some evidence that THC may be medically useful as a treatment for

Answer 42

- anorexia - pain - emesis

Question 43

According to the 2011 Monitoring the Future survey, approximately ______ of high school seniors reported using marijuana at least once in the past year.

Answer 43

36%

Question 44

In the United States, marijuana use typically involves

Answer 44

joints pipes blunts

Question 45

The FDA has approved medications that contain

Answer 45

THC

Question 46

Worldwide, marijuana is most likely to be used as

Answer 46

plant-based marijuana

Question 47

What is multiple sclerosis? How is marijuana therapeutically useful for this condition?

Answer 47

Multiple sclerosis is an autoimmune disease that affects the central nervous system. The disease process elicits inflammation, which damages myelin and slows neural transmission. It is a chronic disease with no known cure. Marijuana has been shown to have therapeutic potential in treating muscle spasticity and neuropathic pain from this disease.