Chapter 2 Flashcards
Division of nervous system
CNS and PNS
CNS
brain & spinal cord
PNS
somatic & autonomic
Autonomic
sympathetic & parasympathetic
Somatic
movements sk. muscles
Parasympathetic
“homeostasis” rest & digest
3 divisions
hindbrain, mindbrain, forebrain
Hindbrain
basic functions
origin of brain dopamine
heart rate, breathing, muscle memory
Mindbrain
integrate sensory info
location of the center of the reward pathway
Forebrain
higher mental process
two major cell types
neurons & glial cells
Glial cells
physical & functional support provide ATP glial cells wrap around myelin nutrients to neurons remove debris
Microglia
glial causes swelling
Glial cells create
blood-brain barrier
*semi-permeable membrane, only lipophilic drug can pass through
Neurons
4 functional zones: cell body, dendrites, axons, & synapse
dendrites
input
axons
output
synapse
two neurons meet to pass info
Synaptic transmission
presynaptic and postsynaptic cell
Presynaptic
neuron sending info
Action potential
- change in electrical charge down the length of the axon resulting in NT release
- presynaptic neuron releases NT
- NT binds to a receptor on postsynaptic neurons
- remains in synaptic cleft (gap)
Lost & key
NT fits like key
-drugs mimicks
General drugs effects on Receptors
drugs that cross the blood brain barrier also bing to receptors
-agonist or antagonist
Agonist
agonist drugs increase the effectiveness of neurotransmission
ex. if it increases dopamine’s action, like meth
Antagonist
antagonist drugs decreases the effectiveness of neurotransmission
ex. if it decreases dopamine action call it dopamine antagonist, it blocks NT (helpful)
Neurotransmitters
Excitatory, Inhibitory
Excitatory
increases the normal activity of postsynaptic cell
Inhibitory
decreases the activity of the postsynaptic cell