Mannitol

Question 1

Mannitol (Osmotrol)

Class

Answer 1

Osmotic diuretic

Question 2

Mannitol (Osmotrol)

Mechanism of Action

Answer 2

Decreases cellular edema, increases urinary output

Question 3

Mannitol (Osmotrol)

Indications

Answer 3

Acute cerebral edema, blood transfusion reactions

Question 4

Mannitol (Osmotrol)

Contraindications

Answer 4

Pulmonary edema, patients who are dehydrated, hypersensitivity

Question 5

Mannitol (Osmotrol)

Adverse Reactions

Answer 5

Pulmonary congestion, sodium depletion, transient volume overload

Question 6

Mannitol (Osmotrol)

Drug Interactions

Answer 6

May enhance digitalis toxicity

Question 7

Mannitol (Osmotrol)

Adult Dosage

Answer 7

1.5 – 2 g/kg IV slow push or infusion

Question 8

Mannitol (Osmotrol)

Pediatric Dosage

Answer 8

0.25 – 0.5 g/kg IV or 60 minutes

Question 9

Mannitol (Osmotrol)

Onset

Answer 9

15 minutes after start of infusion

Question 10

Mannitol (Osmotrol)

Peak Effect

Answer 10

30 – 60 minutes

Question 11

Mannitol (Osmotrol)

Durations

Answer 11

3 – 8 hours after discontinued