Magnesium Sulfate Flashcards
Magnesium Sulfate
Adult Dosage
Seizure activity associated with pregnancy:
1 – 4 g IV/IO over 3
minutes; maximum dose of 30 – 40 g/day
Magnesium Sulfate
Adult Dosage
Torsades de pointes or cardiac arrest due to hypomagnesaemia:
1 -2 g diluted in D5W IV/IO over 5 – 20 minutes.
Magnesium Sulfate
Adult Dosage
Torsades de pointes w/ a pulse or AMI w/ hypomagnesaemia:
Loading dose of 1 – 2 g mixed in 50 – 100 mL D5W over 50 – 60 minutes IV. Follow with 0.5 – 1 g/hr IV titrated to effect.
Magnesium Sulfate
Asthma:
1-2 g mixed in 50-100 ml given over 10-20 mins
Magnesium Sulfate
Pediatric for Torsades
IV/IO infusion: 25 – 50 mg/kg over 10 – 20 minutes; faster if
treating Torsade de pointes.
Magnesium Sulfate
Pediatric Dose for asthma:
25 – 50 mg/kg over 10 – 20 minutes
Magnesium Sulfate
Onset IV/ IO
IV/IO immediate
Magnesium Sulfate
Duration IV/ IO
IV/IO 30 minutes
Magnesium Sulfate
Special Considerations
Use with caution in patients with renal failure
Magnesium Sulfate
Onset IM
IM 3 – 4 hours
Magnesium Sulfate
Duration IM
IM 3 -4 hours
Magnesium Sulfate
Class
Electrolyte
Magnesium Sulfate
Mechanism of Action
- Reduces striated muscle contractions and blocks peripheral neuromuscular transmission by reducing acetylcholine release at the myoneural junction
- manages seizure in toxemia of pregnancy, induces uterine relaxation.
- Can cause bronchodilation after beta-agonists and anticholinergics have been used.
Magnesium Sulfate
Indications
Seizures of eclampsia, torsade de points, hypomagnesaemia
Magnesium Sulfate
Contraindications
Heart blocks, myocardial damage, shock
