Mannitol Flashcards

1
Q

Mannitol Trade Name

A

Osmitrol

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2
Q

Mannitol MOA

A

Site of action at glomerulus
Increase in extracellular osmolarity induces movement of intracellular water to extracellular spaces

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3
Q

Mannitol Indications

A

Reduction of intracranial pressure

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4
Q

Mannitol Contraindications

A

Anuria
Renal failure
Intracranial bleeding
Pulmonary congestion

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5
Q

Mannitol Adverse Effects

A

Fluids shifts in combination with renal dysfunction

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6
Q

Mannitol and CPB

A

Diuretic
Oxygen free radical scavenger
Cardioplegia additive

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7
Q

Mannitol Dosing

A

Varies on bypass
12.5 g of 25% mannitol is common

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8
Q

Mannitol Preparation

A

20% 20g/100mL
25% 25g/100mL

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9
Q

Mannitol Drug Class

A

Osmotic diuretic

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