Dopamine

Question 1

Dopamine Indications

Answer 1

Improve hemodynamic status in shock patients due to reduced CO

Question 2

Dopamine Preparation

Answer 2

40 mg/mL preparation
200mg (5mL) or 400 mg (10mL) vials in a 250 mL or 500 mL solution

Question 3

Dopamine Dosing

Answer 3

2-5 mcg/kg/min
Max 50 mcg/kg/mL

Question 4

Infusion Rate (mL/hour) =

Answer 4

[Dose (mcg/kg/min) * kg * 60 (min/hour)]/concentration (mcg/mL)

Question 5

Dopamine Contraindications

Answer 5

Pheochromocytoma (tumor causing excessive catecholamine production)

Question 6

Dopamine Adverse Effects

Answer 6

Tissue ischemia
Cardiac arrhythmias
Hypotension after abrupt discontinuation

Question 7

Dopamine MOA

Answer 7

Precursor to norepinephrine
beta 1 and alpha 1 receptors

Question 8

Dopamine Drug Class

Answer 8

Catecholamine

Question 9

Dopamine Pharmacodynamics

Answer 9

<5 mcg: vasodilation
5-10 mcg: beta 1 activation, increasing heart rate and contractility
>10 mcg: alpha 1 activation, vasoconstriction