MALIGNANT HYPERTHERMIA

Question 1

Rare, life-threatening complication seen in ..

Answer 1

children and adolescents which may be triggered by drugs used in anesthesia

Question 2

frequently triggered by ?

Answer 2

Halothane (inhalation anethesia) and Succinylcholine (muscle relaxant)

Question 3

Genetically transmitted as ?

Answer 3

a dominant trait (1: 50,000-100,000 anesthesias)

Question 4

May be life-threatening why?

Answer 4

Contracture of skeletal muscles (muscle rigidity), marked temperature elevation (1 degree every 5 minutes), tachycardia, metabolic acidosis, hypoxia

Question 5

May occur during?

Answer 5

induction or maintenance of anesthesia but can also occur postoperatively

Question 6

All OR personnel must be familiar with the protocol of its management

Answer 6

. Treated with immediate infusion of Dantrolene, a muscle relaxant
. The anesthetic that triggered the reaction must be immediately discontinued and patient must be given 100% oxygen
. Relatives of affected patient must be investigated at a later time