Male Reproductive Histology Lab Flashcards
Pale staining cells with a prominent nucleus
Sertoli cell
Cells on basement membrane; mitotic derivatives of primordial germ cells
Spermatogonia
pronounced prophase nucleus, round distinct chromatin profile
primary spermatocyte
In underlying connective tissue adjacent to Sertoli cells –> pale staining cells with eosinophilic cytoplasm
Leydig cells
plexus of testicular veins that traverse the spermatic cord
pampiniform plexus
“hill” in the posterior prostate that marks the site of the entrance of the ejaculatory ducts
seminal colliculus/verumontanum
support cells for spermatogonia and progeny (see below); somatic cells and do not divide after puberty (10% of cells in tubules post puberty)
sertoli cells
become mitotically and meiotically active at puberty and then comprise 90% of cells in tubules
germ cells
2d, 2n
spermatogonia
4d, 2n
Primary spermatocytes
2d, 1n
Secondary spermatocytes
1d, 1n
Spermatids and Spermatozoa
cuboidal epithelium that conducts immature spermatozoa from seminiferous tubules to epididymis
rete testis
produce testosterone under stimulation of LH in late fetal and postnatal state (stimulated by HCG in the placenta)
leydig cells
Leydig cells produce testosterone under the influence of ______
luteinizing hormone
Luteinizing hormone is stimulated by _____ in the early fetus
HCG
Prenatally, ______ suppresses LH production
testosterone
Why don’t any new antigens created in the course of sperm maturation provoke
immune reactions in the mother?
Primary spermatocytes and beyond live within sertoli tight junctions on the bloodless side of the blood-testis barrier
T/F The progeny of a given type A pale
spermatogonium are clonal
T –> and remain connected to each other by bridges of cytoplasm until late in development
lined by pseudostratified low columnar epithelium, some with microvilli, which resorb fluid, and some with sparse cilia that help propel the (as yet) non-motile spermatozoa from seminiferous tubules to ductus epididymis
efferent ductules
lined by tall pseudostratified columnar epithelium with large branched stereocilia [not true cilia as lack microtubules and basal body]). These cells with stereocilia (also known as
principle cells), reabsorb much of the fluid from the lumen, as well as secreting additional components into the luminal fluid.
epididymis
Site of maturation of spermatozoa and where they acquire motility
epididymis
Most prostatic adenocarcinomas arise from glands in the _____ zone
peripheral
Most male urethral obstruction caused by benign overgrowth of glands/stroma in the _____ and _____ zones
transitional and periurethral
Lined by urothelium (transitional epithelium) until very close to penile tip, where stratified squamous mucosa
urethra
accessory male genital glands
seminal vesicles, prostate gland, and bulbourethral glands
