Histology of Female Reproductive System Flashcards
Where in the ovary are follicles found?
cortex/periphery
Where are blood vessels in the ovary?
center/medulla
2 functions of ovaries
egg and hormone production
Germ cell + surrounding cells in ovary
follicle
What kind of epithelia surrounds primordial oocytes?
squamous
What kind of cells are granulosa cells in primary follicles?
cuboidal
After the first meiotic division and division of a polar body, where in the cell cycle is there arrest?
metaphase of meiosis 2
The fibrous _______ encapsulates the ovary
tunica albuginea
The ______ is between the oocyte and follicular/granulosa cells.
zona pellucida
T/F Follicles are vascularized.
F –> protected by basement membrane
Theca folliculi differentiates into two layers:
theca interna and externa
____ cells secrete androstenedione which is transferred to follicular cells for ____ production which is converted to _____.
theca interna –> testosterone –> estradiol
____ is connective tissue capsule-like layer continuous with ovarian stroma.
theca externa
The zona granulosa proliferates t oform a fluid space called ____.
follicular antrum
secondary follicle is defined by a _____ filled with _____ and _____.
antrum filled with glycosaminoglycans and steroid hormones
The mature graafian follicle completes the first meiotic division right before ____
ovulation
The fluid filled antrum of a graafian follicle is surrounded by _____
corona radiata
Process by which oocyte and granulosa cells degenerate.
atresia
T/F atresia can occur at any time
T
Early/advanced atresia is characterized by a thickening of hte basement membrane between granulosa cells and theca interna called glassy membrane.
Advanced atresia
glassy membrane
advanced atresia
In the corpus luteum, follicular/granulosa cells give rise to ______ cells and secrete ____ and ____.
follicular lutein cells and secrete progesterone and estrogen
In corpus luteum, theca interna cells give rise to ______ cells and secrete ____ and ____.
theca lutein cells and secrete androgen precursors and progesterone
Where in the oviduct is the egg picked up?
infundibulum
Where in the oviduct does fertilization take place?
ampulla
Where in the oviduct transports a fertilized egg to the uterus?
isthmus and interstitial
Which part of the oviduct has vascular supporting tissue?
serosa
Mucosal folds of the ___ form a branching core of vascular tissue.
ampulla
T/F Oviduct epithelium has both ciliated and non-ciliated cells.
T
The ____ cells of the ampulla produce a secretion that is propelled towards the uterus.
non-ciliated –> nutritive and protective function for egg and promotes sperm activation
The epithelium of the ampulla is of what kind?
simple columnar
The outer layer of the uterus is called ____
outer serosa/adventitia
The ____ layer of the uterus is smooth muscle
myometrium
The _____ of the uterus consists of epithelium and lamina propia containing simple tubular glands
endometerium
2 components of endometrium
basalis and functionalis
Which part of endometerium is sloughed off each cycle?
functionalis
Which layer of the uterus changes the most during pregnancy?
myometrium
During pregnancy, myometrium expands by what processes?
hypertrophy, hyperplasia, increase in collagen
The ____ endometrium involves proliferation of stroma and extension of glands to hte surface – correlated with estrogen release from developing follicles.
proliferative endometrium
____ endometrium is marked by ovulation and production of glycogen-rich secretion correlated with progesterone secretion.
secretive endometrium
Which layer of the vagina is stratified squamous with a glycogen lamina propria and loose connective tissue?
mucosa
Which layer of the vagina has dense connective tissue rich in elastic fibers?
adventitia
T/F vagina wall has glands
F –> mucus comes from uterine cervix
At what point in time do epithelial cells around ducts in breasts proliferate?
pubery
During pregnancy ____ proliferate at the ends of the ducts in breast.
alveoli
Milk secretion and accumulation occurs in the alveolar ____.
lumen
What products constitute milk produced during lactation?
lipid droplets, caseins, alpha-lactalbumin
During lactation, proteins are released into the alveolar lumen by what process?
exocytosis
