MALARIAL PARASITES (PLASMODIUM SPP) Flashcards

1
Q

Sexual Phases

A
  • Female Anopheles Mosquito (DH)
  • Sporogony/Sporogonic Cycle
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2
Q

Asexual Phase

A
  • Man or other vertebrates (IH)
  • Schizogony (Erythrocytic/Exo-Erythrocytic)
  • Gametogony (Merogony)
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3
Q

sleeping or dormant forms; causes relapse of the disease when reactivated

A

hypnozoites

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4
Q

these reinvade the hepatocytes following rupture of schizont

A

vivax and ovale

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5
Q

microgametocytes

male or female

A

male

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6
Q

macrogametocytes

male or female

A

female

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7
Q

age of RBC infected in P. falciparum

A

ALL

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8
Q

age of RBC infected in P. vivax

A

Young

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9
Q

age of RBC infected in P. ovale

A

Young (Retics)

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10
Q

age of RBC infected in P. malariae

A

Mature

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11
Q

appearance of parasitized RBC in P. falciparum

A

Normal; multiple
infection of RBC very
common

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12
Q

Appearance of
parasitized RBC in P. vivax

A

Larger than normal,
pale, and oval to
normal in shape

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13
Q

Appearance of
parasitized RBC P. ovale

A

Larger than normal,
oval and may have
fimbriated edges

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14
Q

Appearance of
parasitized RBC P. malariae

A

Normal in shape; size
may be normal or
slightly smaller

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15
Q

RBC stippling in P. falciparum

A

Maurer’s dot’s (occasionally seen)

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16
Q

RBC stippling in P. vivax

A

Schuffer’s dots (commonly/routinely seen)

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17
Q

RBC stippling in P. ovale

A

Schuffer’s/James dots

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18
Q

RBC stippling in P. malariae

A

Ziemann’s dots rarely seen

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19
Q

Stages in the peripheral blood P. falciparum

A

Rings, gametocytes

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20
Q

Stages in the peripheral blood P. vivax, P. ovale, P. malariae

A

Rings, mature trophozoite (schizont gametocytes)

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21
Q
A
22
Q

Length of erythrocytic cycle in P. falciparum

A

36-48 hrs

23
Q

Length of erythrocytic cycle P. vivax

A

48 hrs

24
Q

Length of erythrocytic cycle P. ovale

A

48 hrs

25
Q

tertian malarias

A

P. falciparum, P. vivax, P. ovale

26
Q

Length of erythrocytic cycle P. malariae

A

72 hrs

27
Q

Length of erythrocytic cycle is based on what

A

paroxysm

28
Q

disease caused by P. falciparum

A

malignant tertian malaria

29
Q

black water fever

A

P. falciparum

30
Q

disease caused by P. vivax

A

Benign tertiary malaria

31
Q

disease caused by P. ovale

A

ovale tertian malaria

32
Q

disease caused by P. malariae

A

Quartan malaria

33
Q

true or false

P. falciparum mature trophozoites and schizonts are rarely found in the peripheral blood because they are sequestered in the deep vasculature (small blood vessels of internal organs) where schizogony occurs.

A

true

34
Q

banana shaped Plasmodium

A

P. falciparum (unique)

35
Q

daisy formation of merozoites

A

P. malariae

36
Q

incubation period of malaria

A

8-40 days

37
Q

classical sign of malaria; characterized by chills, fever, and profuse sweating

A

paroxysm

38
Q

recurrence of paroxysm

A

periodicity

39
Q

every 24 hrs

A

Quotidian

40
Q

Quotidian Malaria

A

Plasmodium knowlesi

41
Q

Every 48 hrs

A

tertian malaria

42
Q

tertian malaria

A

P. falciparum, P. vivax, P. ovale

43
Q

Every 72 hrs

A

Quartan malaria

44
Q

Quartan malaria

A

P. malariae

45
Q

most fatal type caused by Plasmodium falciparum

A

Malignant tertian malaria

46
Q

manifestations of malignant tertian malaria

A
  • black water fever
  • intravascular hemoglobinuria
  • from red urine to brown’s black
47
Q

resistance to P. falciparum may be due to

A

sickle cell trait

48
Q

Fy (a-b-) resistance to P. vivax

A

Duffy negative blood group

49
Q

parasite of monkeys

A

Plasmodium knowlesi

50
Q

Simian/5th Human Malaria

A

Plasmodium knowlesi

51
Q

young P. knowlesi resembles __________; while mature forms resemble _______

A

P. falciparum; P. malariae

52
Q

relapse may occur with _______ infections due to reactivation of _________ in the liver

A

P. vivax and P. ovale; hypnozoites