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PARASITOLOGY > HEMOFLAGELLATES > Flashcards

HEMOFLAGELLATES Flashcards

1
Q

Hemoflagellates

A
  • Leishmania spp
  • Trypanosoma brucei complex
  • Trypanosoma cruzi
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2
Q

MOT and vector of Leishmania spp

A

MOT: skin innoculation of promastigote
Vector: sandflies (phlebotomous/lutzomyia)

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3
Q

infective stage of Leishmania

A

promastigote

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4
Q

MOT and vector of Trypanosoma brucei complex

A

MOT: skin inoculation of metacyclic/metacystic trypomastigotes

Vector: tsetse flies (Glossina spp)

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5
Q

composed of 2 or more organisms that share a common biology

A

Trypanosoma brucei complex

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6
Q

MOT and vector of Trypanosoma cruzi

A

MOT: indirect inoculation of metacyclic/ metacystic trypomastigote
Vector: feces of Kissing/ Redwiid/ Triatomine bugs

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7
Q

habitat of Leishmani spp

A

lymphoid tissues of the skin mucus, membranes, visceral organ (liver, spleen lymphq

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8
Q

habitat of T. brucei complex

A

Blood, lymph, CSF

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9
Q

habitat of T. cruxi

A
  • Endothelial cells, muscles, nervous tissues (amastigotes)
  • Blood, CSF (trypomastigote)
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10
Q

developmental stages of Hemoflagellates

A

PAMET

P - PROMASTIGOTE
A - AMASTIGOTE
M- METACYCLIC TRYPOMASTIGOTE
E- EPIMASTIGOTE
T- TRYPOMASTIGOTE

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11
Q

vector of Leishmania spp

A

sandfly

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12
Q

developmental stages of Leishmania spp

A

PA
- Promastigote (sandfly)
- Amastigote (man)

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13
Q

vector or T. brucei

A

Tsetse fly

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14
Q

developmental stages present in T. brucei

A

MET
- Metacyclic Trypomastigote (tsetse fly)
- Epimastigote (tsetse fly)
- Trypomastigote (man)

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15
Q

vector of T. cruzi

A

kissing, redwiid, triatomine bugs

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16
Q

developmental stages present in T. cruzi

A

AMET
- Amastigote (man)
- Metacyclic Trypomastigote (bug feces)
- Epimastigote (bug)
- Trypomastigote (man)

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17
Q

Skin lesions with elevated margins that leave ugly scars on healing

A

Cutaneous Leishmaniasis

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18
Q

Old World CL

A

Leishmania tropica, L. major

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19
Q

New World CL

A

L. mexicana

20
Q

vector of L. mexicana

A

Lutzomyid fly

21
Q

oriental sore, delhi ulcer, aleppo, jericho, baghdad bol

A

old world CL

22
Q

Chiclero’s ulcer

A

New World CL

23
Q

specimen diagnosis of Cutaneous Leishmaniasis

A

skin biopsies from margin of ulcer

24
Q

Highly disfiguring, leprosy-like cutaneous lesions that spread to the mucous membranes

A

Muco-cutaneous Leishmaniasis

25
Q

agent/s of Muco-cutaneous Leishmaniasis

A

L. braziliensis

26
Q

spx for Muco-cutaneous Leishmaniasis

A

Skin and mucosal biopsy

27
Q

aka espundia/tapir’s nose

A

Muco-cutaneous Leishmaniasis

28
Q

fever, organomegaly, ascites, anemia, hyperpigmentation of the skin

A

Visceral Leishmaniasis

29
Q

Old World VL

A

L. donovani

30
Q

old world VL aka

A
  • kala-azar
  • dum-dum
  • black fever
31
Q

New World VL

A

L. chagasi

32
Q

spx for Visceral
Leishmaniasis

A

tissue aspirates or biopsy (liver, spleen, bone marrow)

33
Q

enlargement of abdomen due to fluid accumulation

A

ascites

34
Q

hyperpigmentation of the skin

A

black fever (darkening)

35
Q
  • Trypanosome chancre (at the bite site)
  • Hemolymphatic stage (invasion of blood in lymphatic system)
  • fever and cervical lymphadenopathy winter bottom sign
  • Meningoencephalitic or sleeping stage
    – somnolence, coma, and death
A

African Trypanosomiasis
or Sleeping Sickness

36
Q

swollen neck lymph node

A

winterbottom sign

37
Q

WEST African Trypanosomiasis or Sleeping Sickness

A

T. brucei gambiense (Chronic)

38
Q

EAST African Trypanosomiasis or Sleeping Sickness

A

T. brucei rhodesiense (acute)

39
Q

spx for african
Trypanosomiasis
or Sleeping
Sickness

A
  • blood specimen
  • lymph node aspirate
  • CSF
40
Q

New World or American Trypanosomiasis

A

Chaga’s disease

41
Q

agent of Chaga’s disease

A

T. cruzi

42
Q

swelling around the eyes (orbital edema)

A

Romania

43
Q

swelling at other sites aside the eyes

A

chagoma

44
Q

manifestations of chaga’s disease

A

fever, hepatosplenomegaly, myocarditis

45
Q

spx for chaga’s disease

A

blood, biopsy from affected organs (muscles and nervous tissues)

PARASITOLOGY (25 decks)

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