Magnesium Sulfate

Question 1

What is MgSO4?

Answer 1

Magnesium Sulfate

Question 2

What is the brand name for MgSO4?

Answer 2

Same as generic name

Question 3

What drug class is MgSO4?

Answer 3

Electrolyte

Question 4

Mechanism of action of MgSO4?

Answer 4

Blocks release of acetylcholine @ the myoneural junction. This results in smooth muscle relaation in bronchoconstriction and uterine contractions. Stabilizes cardia myocyte in torsades.

Question 5

Indications for MgSO4

Answer 5

Torsades, eclamptic seizures, premature labor, bronchospasm refractory (ineffective) to Beta2 agonists

Question 6

Contraindications for MgSO4

Answer 6

heart blocks, myocardial damage

Question 7

adverse effects of MgSO4

Answer 7

CNS depressant, respiratory depression, AV block, hypotension, vasodilation, hyporefelxia (absence of reflexes)

Question 8

Precautions of MgSO4

Answer 8

may enhance effects of other CNS depressants

Question 9

Dose and admin for MgSO4 for eclamptic seizures

Answer 9

1-4g over 3mins

Question 10

Dose and admin for MgSO4 for torsades

Answer 10

1-2g. IVP over 5-20mins if they are stable

Question 11

Dose and admin for MgSO4 for asthma

Answer 11

25-50mg/kg in 100mL NS over 15-30mins