Concepts Flashcards
What is the neurotransmitter for the parasympathetic system?
Acetylcholine
What does the nicotinic receptor do?
Allows for muscle contraction
What does the muscarinic G1 receptor do?
GI stimulation (SLUDGEM)
What does the muscarinic M2 do?
Surpresses the Chronotropic, dronotropic, and inotropic (causing hypotension and bradycardia)
Which neurotransmitters do the parasympathetic and sympathetic system make?
Parasympathetic: cholinergic
Sympathetic: andregenic
What does Alpha1 do?
vasoconstriction
What does Alpha2 do?
Insulin restriction, glucagon secretion, and inhibits norepi release
What does Beta1 do?
Chronotropic, inotropic, and dromotropic effects. Renin secretion for urinary retention
What does Beta2 do?
Bronchodilator, insulin secretion, arterial dilation in certain key organs
What does the Dopaminergic receptor do?
Vasodilation of renal and mesenteric arteries
What happens during glucogenesis?
When there is extra glucose, it stimulates insulin production, which is converted into glycogen and stored in the liver.
What happens during glucogenolysis?
When there is low sugar, it stimulates glucagon production. It also pulls glycogen from the liver and breaks it down into glucose for use.
What is the protein attached to an activated platelet that sticks? What is the receptor?
Glycoprotein. IIb IIIa receptors
What does Amyl Nitrate plus Sodium Nitrate do?
It binds to cyanide. Sodium Thiosulfate is then given to convert cyanide into a neutral state (thiocyanate) which is excreted by the kidneys.
How does methemoglobins work in reversing the effects of cyanide?
Methemoglobins have a greater affinity for cyanide than cyanide does for the mitochondria in the cell.
