M5 U2 Urinary System Flashcards

1
Q

URINARY SYSTEM Consists of

A

two kidneys
two ureters
one urinary bladder
one urethra.

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2
Q

principal organs of the urinary system

A

kidneys

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3
Q

kidneys process and form ___ as a waste to be excreted.

A

urine

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4
Q

what kidney is often slightly larger than
the other

A

left kidney

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5
Q

The medial surface of each kidney has a concave notch called___

Structures enter or leave the kidney through this notch.

A

hilum.

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6
Q

connective tissue that anchors the
kidneys to surrounding structures and also helps maintain their normal positions

A

renal fasciae

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7
Q

outer region

A

Renal cortex

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8
Q

inner region

A

Renal medulla

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9
Q

important functions of kidney

A

filtering the plasma
removing substances from the filtrate at variable rates

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10
Q

critical in controlling the volume and composition of the body fluids.

A

kidneys

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11
Q

the primary means for eliminating
waste products of metabolism that are no longer needed by the body.

A

kidneys

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12
Q

(from the metabolism of amino acids)

A

urea

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13
Q

(from muscle creatine)

A

creatinine

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14
Q

(from nucleic acids)

A

uric acid

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15
Q

Responsible for regulation of long-term arterial pressure by excreting variable amounts of
sodium and water.

A

KIDNEYS

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16
Q

Responsible for short-term arterial pressure regulation by secreting renin (Renin-Angiotensin-aldosterone system, RAAS).

A

KIDNEYS

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17
Q

contribute to acid-base regulation, along with the lungs, by excreting acids and by regulating the body fluid buffer stores.

A

KIDNEYS

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18
Q

only means of eliminating from the body certain types of acids, such as sulfuric acid and
phosphoric acid, generated by the metabolism of proteins.

A

KIDNEYS

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19
Q

Kidneys secrete ____ (along with the liver), which stimulates the production of red blood cells by hematopoietic stem cells in the bone marrow

A

erythropoietin

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20
Q

develops as a result of decreased erythropoietin
production.

A

severe anemia

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21
Q

essential for normal calcium deposition
in bone and calcium reabsorption by the
gastrointestinal tract.

A

Calcitriol

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22
Q

The kidneys synthesize glucose from amino acids and other precursors during prolonged fasting, a process referred to as

A

gluconeogenesis.

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23
Q

enough potassium, acids,
fluid, and other substances accumulate in the body to cause death within a few days,

A

complete renal failure

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24
Q

homeostatic functions are disrupted and
severe abnormalities of body fluid volumes and
composition rapidly occur.

A

kidney disease or acute failure of the kidneys

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25
functional unit of the kidney.
NEPHRON
26
Each kidney in the human contains about ___ to __ nephrons
800,000 to 1,000,000 nephrons,
27
nephron consists of two parts:
Renal corpuscle Renal tubule
28
where blood plasma is filtered
Renal corpuscle
29
Where the glomerular filtrate (filtered fluid) passes
Renal tubule
30
Nephrons whose glomeruli lie in the renal cortex and have short Loops of Henle that penetrate a short distance in the medulla
Cortical nephrons
31
-20-30% -Nephrons whose glomeruli lie near the renal medulla, and have long Loops of Henle that dip deeply into the medulla.
Juxtamedullary nephron
32
renal processes:
Glomerular filtration Reabsorption of substances from the renal tubules into the blood Secretion of substances from the blood into the renal tubules
33
The fluid that enters the capsular space is called the
glomerular filtrate
34
Blood pressure in glomerular capillaries promotes filtration by forcing water and solutes in blood plasma through the filtration membrane 55 mmHg
Glomerular blood hydrostatic pressure (GBHP)
35
hydrostatic pressure exerted against the filtration membrane by fluid already in the capsular space and renal tubule CHP opposes filtration and represents a “back pressure” of about 15 mmHg
Capsular hydrostatic pressure (CHP)
36
due to the presence of proteins such as albumin, globulins, and fibrinogen in blood plasma, also opposes filtration 30 mmHg
Blood colloid osmotic pressure (BCOP)
37
occurs to Waste products such as Creatinine
Substance is freely filtered but not reabsorbed
38
Typical for electrolytes such as sodium and chloride
The substance is freely filtered, but part of the filtered load is reabsorbed back in the blood
39
occurs to Nutritional substances in the blood, such as amino acids and glucose
The substance is freely filtered but is not excreted in the urine because all the filtered substance is reabsorbed from the tubules into the blood
40
Often occurs for organic acids and bases
The substance is freely filtered and is not reabsorbed but is secreted from the peritubular capillary blood into the renal tubules.
41
successive parts of the tubule before it is excreted as urine:
proximal convoluted tubule the loop of Henle the distal convoluted tubule the collecting tubule the collecting duct
42
The largest amount of solute and water reabsorption from filtered fluid occurs in the proximal convoluted tubules
Proximal convoluted tubule
43
Proximal convoluted tubule reabsorbs
65% of the filtered water, Na+ and K+ 100% of organic solutes such as glucose and amino acids 50% of the filtered Cl-, urea 80-90% of the filtered Ca2+, Mg2+, and HPO42−
44
Proximal convoluted tubule secretes
H+ NH4+ Urea and creatinine
45
Consists of an descending limb, thin ascending limb, and thick ascending limb
Loop of Henle
46
The nephron loop reabsorbs:
- Descending limb: 15% of the filtered water - Ascending limb 20-30% of the filtered Na+ and K+ 35% of the filtered Cl- 10-20% HCO3- Ca+ and Mg+
47
The early distal convoluted tubule reabsorbs:
10-15% of the filtered water 5% of the filtered Na+ and 5% Cl-
48
A major site for parathyroid hormone to stimulate reabsorption of Ca2+.
Early distal convoluted tubule
49
group of closely packed epithelial cells that is part of the juxtaglomerular apparatus and provides feedback control of GFR and blood flow in this same nephron.
macula densa
50
the amount of water and solute reabsorption and the amount of solute secretion vary depending on the body’s needs in the
the late distal convoluted tubules collecting ducts
51
reabsorb Na+ and secrete K+. These cells also have receptors for aldosterone and antidiuretic hormone (ADH).
principal cells
52
reabsorb HCO3− and secrete H+, thereby playing a role in blood pH regulation. In addition, the intercalated cells reabsorb K+.
intercalated cells
53
Found at the point where the afferent arteriole brushes past the distal tubule This structure is important in maintaining homeostasis of blood flow because it reflexively secretes renin when blood pressure in the afferent arteriole drops
JUXTAGLOMERULAR APPARATUS
54
Mechanoreceptors Sensitive to increased pressure in the arteriole
Juxtaglomerular cells
55
Tightly-packed structure made up of distal tubule cells that act as Chemoreceptors Can sense the concentration of solute materials in the fluid passing through the tubule
Macula densa
56
A straight tubule joined by the distal tubules of several nephrons
COLLECTING DUCT
57
reabsorbs water through osmosis only in the presence of ADH
COLLECTING DUCT
58
Tubes that actively convey urine from the kidneys to the urinary bladder
URETERS
59
Runs obliquely through the bladder wall and opens at lateral angles. Because of its oblique course, the ends of the tubes close, acting as valves when the bladder is full, thus preventing backflow of urine
URETERS
60
A muscular, collapsible bag
URINARY BLADDER
61
The wall of the bladder is made mostly of smooth muscle tissue, called the
detrusor muscle
62
the bladder is lined with
mucous transitional epithelium that forms rugae
63
allows the bladder to distend considerably.
rugae,
64
Serves as a reservoir for urine before it leaves the body
URINARY BLADDER
65
The mechanism for voiding urine begins with the voluntary relaxation of the external sphincter muscle of the bladder
MICTURITION
66
This forces urine out of
MICTURITION
67
Involuntary micturition is called
incontinence
68
small tube lined with mucous membrane leading from the floor of the bladder (trigone) to the exterior of the body
urethra
69
passes through the center of the prostate gland, just after leaving the bladder.
male urethra