M2. Immunoprophylaxis

Question 1

Protection against infectious diseases through immunity acquired either passively or actively.

Answer 1

Immunoprophylaxis

Question 2

when antibodies are transferred from mother to

fetus (IgG) or in colostrum (IgA)

Answer 2

Naturally acquired

Question 3

short-term by injection of antibodies, e.g. giving
of antitoxin for treatment of diphtheria,
botulinum or tetanus

Answer 3

Artificially acquired

Question 4

Live microorganism has lost its virulence and does not

produce disease, only immunity

Answer 4

Live attenuated

Question 5

Virulent bacteria or viruses are killed by heat or
chemicals
• Do not stimulate local immunity
• short lastin

Answer 5

Killed vaccines

Question 6

• Prepared by detoxifying bacterial toxins
• Bacterial exotoxins treated by formalin to destroy
toxicity and retain antigenicity

Answer 6

Toxoids

Question 7

Microbial polypeptides are isolated from

infective material

Answer 7

Subunit vaccines

Question 8

Antigens are synthesized by inserting the coding

genes into E. coli or yeast cell

Answer 8

Recombinant DNA derived antigen vaccines

Question 9

The genes coding for the antigen is inserted into

the genome of an avirulent vector

Answer 9

Recombinant DNA avirulent vector vaccines