LYSOSOMES Flashcards
In which cells lysosomes are found in abundance ?
They are abundant in the cells which are mainly involved in phagocytosis. example - macrophages.
What are lysosomes
They are the polymorphic cell organelles of the cell
What is the structure of the lysosomes ?
- Single membrane bound structure
- pH =< 5 (acidic)
- Have the abundance of hydrolytic enzyme such as lipases , protases , phosphatases , sulphatases , amylase etc.
What is the origin of lysosomes ?
Origin :- GERL
What is the marker enzyme of the lysosomes ?
ACID PHOSPHATASE
What are the types of the lysosomes ?
- Primary lysosomes
2. Secondary lysosomes
What are primary lysosomes ?
- They are formed by the Golgi body
2. They contain inactive enzyme
What are secondary lysosomes and what are its types ?
- They are formed from type primary lysosomes due to budding
- They contain active enzyme
- They are of 4 types namely
a) Phagosome
b) Autophagosome
c) Residual body
d) Autophagic vacuole
What are phagosomes ?
Secondary lysosomes associated with the foreign body
What are autophagosome ?
Secondary lysosome associated with the old and dead cell organelles
What are residual bodies ?
Secondary lysosome containing the undigested waste
It generally comes near to PM and discharge all its content outside the cell (exocytosis)
What is polynephrites ?
Sometime when residual body fails to do the discharge of its content and they instead load the cell and bring aging in the cell .
Absent of ephagy in the cell is known as polynephrites
In which diseases polynephrites can result in to
?
- Gout
- Arthritis
- Cystic fibrosis
What is the autophagic vacuole ?
- It is formed by the cluster of several primary lysosome near the waste and they surround it like vacuolar membrane and bring about its autolysis or auto digestion.
LEARN THE EXAMPLE OF THE AUTOPHGIC VACOULE FROM NOTE
DONE :D
