lymphoma Flashcards
what
cancers affecting lymphocytes inside lymphatic system
cancer cells proliferate inside lymph nodes
Hodgkin’s lymphoma
caused by proliferation of lymphocytes
Hodgkin’s lymphoma : ages affected
bimodal peak
20yrs and 75yrs
Hodgkin’s lymphoma: risk factors
HIV
EBV
autoimmune e.g. RA, sarcoid
FHx
Hodgkin’s lymphoma: presentation
lymphadenopathy B symptoms fatigue itching SOB abdo pain recurrent infections
b symptoms
fever
weight loss
night sweats
Hodgkin’s lymphoma: Ix
LDH
lymph node biopsy
Hodgkin’s lymphoma: key finding from lymph node biopsy
reed-sternberg cells
reed-sternberg cells
abnormally large B cells
multiple nuclei with nucleoli within them
(appearance of face of owl with large eyes)
Ann Arbor staging: 1
confined to one region of nodes
Ann Arbor staging: 2
in more than one region but same side of diaphragm
Ann Arbor staging: 3
affects lymph nodes above and below diaphraghm
Ann Arbor staging: 4
widespread involvement incl non lymphatic organs e.g. lung, liver
Hodgkins Lymphome Mx
chemo
radiotherapy
Non-Hodgkin Lymphoma: risk factors
HIV EBV h.pylori hep B or c FHx