lymphoma Flashcards

1
Q

what

A

cancers affecting lymphocytes inside lymphatic system

cancer cells proliferate inside lymph nodes

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2
Q

Hodgkin’s lymphoma

A

caused by proliferation of lymphocytes

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3
Q

Hodgkin’s lymphoma : ages affected

A

bimodal peak

20yrs and 75yrs

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4
Q

Hodgkin’s lymphoma: risk factors

A

HIV
EBV
autoimmune e.g. RA, sarcoid
FHx

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5
Q

Hodgkin’s lymphoma: presentation

A
lymphadenopathy 
B symptoms 
fatigue 
itching 
SOB 
abdo pain 
recurrent infections
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6
Q

b symptoms

A

fever
weight loss
night sweats

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7
Q

Hodgkin’s lymphoma: Ix

A

LDH

lymph node biopsy

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8
Q

Hodgkin’s lymphoma: key finding from lymph node biopsy

A

reed-sternberg cells

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9
Q

reed-sternberg cells

A

abnormally large B cells
multiple nuclei with nucleoli within them

(appearance of face of owl with large eyes)

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10
Q

Ann Arbor staging: 1

A

confined to one region of nodes

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11
Q

Ann Arbor staging: 2

A

in more than one region but same side of diaphragm

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12
Q

Ann Arbor staging: 3

A

affects lymph nodes above and below diaphraghm

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13
Q

Ann Arbor staging: 4

A

widespread involvement incl non lymphatic organs e.g. lung, liver

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14
Q

Hodgkins Lymphome Mx

A

chemo

radiotherapy

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15
Q

Non-Hodgkin Lymphoma: risk factors

A
HIV 
EBV
h.pylori
hep B or c
FHx
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