ITP

Question 1

what

Answer 1

immune mediated reduction in platelet count

example of TII hypersensitivity reaction

Question 2

kids vs adult

Answer 2

in children is typically more acute

Question 3

ITP in children - may follow

Answer 3

an infection or vaccination

Question 4

ITP in children - features

Answer 4

bruising
petechial/purpural rash
bleeding - epistaxis

Question 5

ITP in children - FBC

Answer 5

isolated thrombocytopenia

Question 6

ITP in children - when is bone marrow examination required

Answer 6

if atypical features

• lymphadenopathy
• splenomegaly
• high/low WCC
• failure to resolve

Question 7

ITP in children - Mx

Answer 7

usually no treatment required

advice to avoid activities that may result in trauma

Question 8

ITP in children - Mx - platelet count <1/signif bleeding

Answer 8

steroids

IvIG

Question 9

ITP in adults - presentation

Answer 9

incidental finding following routine bloods

petichiae, purpura
bleeding

Question 10

ITP in adults - Mx

Answer 10

1/ oral prednisolone

2/ IVIg

Question 11

Evan’s syndrome

Answer 11

ITP in assoc with auotimmune haemolytic anaemia