essential thrombocytosis Flashcards
1
Q
what
A
myeloproliferative disorder
dysregulated megakaryocyte proliferation
2
Q
hallmark
A
raised platelet count
3
Q
symptoms
A
thrombosis - arterial or venous
bleeding - GI, intracranial
headache
dizziness/syncope
4
Q
signs
A
splenomegaly
erythromelalgia
livedo reticularis
5
Q
erythromelalgia
A
red/blue discolourisation extremeties
often assoc with burning pain
6
Q
Mx
A
hydroxycarbamide
aspirin