essential thrombocytosis Flashcards

1
Q

what

A

myeloproliferative disorder

dysregulated megakaryocyte proliferation

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2
Q

hallmark

A

raised platelet count

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3
Q

symptoms

A

thrombosis - arterial or venous
bleeding - GI, intracranial
headache
dizziness/syncope

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4
Q

signs

A

splenomegaly
erythromelalgia
livedo reticularis

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5
Q

erythromelalgia

A

red/blue discolourisation extremeties

often assoc with burning pain

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6
Q

Mx

A

hydroxycarbamide

aspirin

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