Lymphatic System Flashcards

1
Q

How does the lymphatic system maintain homeostasis?

A

By eventually returning most of the fluid that has been diverted back into the blood

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2
Q

What is lymph?

A

Watery solution that flows through the lymphatic system

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3
Q

What does most lymph start out as?

A

Blood plasma that is forced out of capillaries, where leakage helps exchange of nutrients and gases between blood in capillaries and cells in tissues

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4
Q

What do the lymph nodes do?

A

Monitor and cleanse lymph as it filters through

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5
Q

Give four examples of lymphoid organs

A

Spleen
Thymus
Adenoids
Tonsils

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6
Q

What are the lymphatic capillaries made of?

A

Loosely overlapping endothelial cells that has flap-like mini valve that ensures lymph fluid won’t leak back into the interstitial space

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7
Q

What does the right lymphatic duct drain?

A

Lymph collected from the upper right area of the torso, arm and right side of the head and thorax

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8
Q

What can blockage of the lymph system lead to?

A

Lymphedema

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9
Q

What does MALT stand for?

A

Mucosa-associated lymphoid tissues

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10
Q

Where are MALTs found?

A

In mucous membranes around the body eg. Tonsils, Peyer’s patches and the appendix

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11
Q

What three things help propel lymph along?

A

Skeletal muscle movement
Pressure change in the thorax
Pulsations of adjacent arteries

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12
Q

What does GALT stand for?

A

Gut associated lymphatic tissue

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13
Q

What does BALT stand for?

A

Bronchus associated lymphatic tissue

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14
Q

What is the hilum?

A

Indentation in the surface of a kidney, spleen or other organ where blood vessels, ducts, nerve fibres etc enter or leave it

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15
Q

Where are follicular dendritic cells found?

A

Germinal centres

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16
Q

What do follicular dendritic cells cause?

A

Proliferation of B cells, in particular memory B cells

17
Q

What is the term given for enlarged lymph nodes?

A

Lymphadenopathy

18
Q

What causes lymphadenopathy?

A

As nodes fight infection, germinal centres fill with increasing numbers of lymphocytes, causing lymph nodes to swell

19
Q

What are the immune functions of the spleen?

A

Antigen presentation by APCs
Activation and proliferation of B and T lymphocytes, production of antibodies
Removal of macromolecular antigen from blood

20
Q

What are the haemopoietic functions of the spleen?

A

Removal and destruction of old, damaged and abnormal erythrocytes
Retrieval of iron from erythrocyte Hb

21
Q

How can a ruptured spleen lead to death?

A

Through exsanguination (severe blood loss)

22
Q

Where is the thymus located?

A

In the superior mediastinum

23
Q

What is the role of the thymus?

A

Maturation of bone marrow derived stem cells into T cells (this is called thymic cell education)

24
Q

When might the spleen enlarge?

A

In response to systemic infection (glandular fever, malaria and septicaemia)