Adaptive Immunity Flashcards
What is another name for adaptive immunity?
Specific immune response
True or false: you are born with adaptive immunity
FALSE
What are the differences between the adaptive and innate defence systems?
The adaptive system has the ability to remember specific pathogens
The adaptive system is systemic rather than being restricted to a particular infection
Complete the sentence:
Antibodies are produced by _ lymphocytes, which transform into ______ cells that synthesise and secrete a specific antibody.
B
Plasma
Where are B lymphocytes produced and where do they mature?
Bone marrow
When a complementary shaped antibody binds to an antigen and becomes activated, the B cell starts cloning and can become one of which two type of cells?
Effector cells
Memory cells
True or false: effector cels are packed with extra RER which act as an antibody factory
TRUE
Define neutralisation
Antibodies block the binding site of a pathogen
What is the term given to antibodies that can bind to multiple antigens at once?
Agglutination
How do babies receive passive humoural immunity?
Through the placenta and breast milk
Which lymphocytes are involved in the cellular immune response?
T lymphocytes
What do T lymphocytes do? (3)
Cause inflammation
Activate macrophages
Regulate much of the immune response
Which cells wear the MHC2 protein? (3)
Macrophages
Dendritic cells
B cells
What is the difference between the MHC1 and MHC2 proteins?
Class 2 MHC proteins bind to fragments of exogenous antigens like viruses that have been engulfed, broken up and displayed to get the attention of other cells
Normal, nucleated cells have MHC1 protein on their surface and these present short AA chains based on endogenous proteins
Where are T cells produced and where do they mature?
Produced in the bone marrow but mature in the thymus
