Cell Death Flashcards
1
Q
What are the two ways in which cells can die?
A
Necrosis and apoptosis
2
Q
Why do necrotic cells swell and burst?
A
Failure of action of the Na+/K+ ATPase pump
3
Q
What causes necrosis?
A
Physical disruption to the cell through injury, bacterial toxins or nutritional deprivation
4
Q
What happens during necrosis? (5)
A
- Cell loses functional control
- Osmotic pressure causes swelling in organelles
- Chromatin clumps
- Cell eventually bursts (lysis)
- Cytotoxic cellular components spill out from membrane, inducing tissue damage and inflammation
5
Q
What is apoptosis?
A
Natural cell death
