lymphatic and immune system Flashcards
organs part of the lymphatic system
thymus, adenoids, bone marrow
secondary- lymph nodes, spleen, tonsils (where B & T cells reside)
organs of the immune system
skin, bone marrow, spleen, lymph nodes, thymus, tonsils, mucous membranes, peyers patches, appendix
functions of the lymphatic system
carries out excess fluids to the bloodstream, filters pathogens from the blood, and transports immune cells
peyers patches
located in the submucosa of the small intestine, they carry B&T cells that flood a channel that connects to lacteal and then to the mesenteric lymph node that addresses
cisterna chyli
major incoming port for lower extremities and mesenteric lymph nodes
functions of the immune system
scavage dead or dying body cells, destroys abnormal cells, protects from pathogens and foreign molecules (parasites, bacteria, viruses)
lines of defense
- non-specific natural barriers which restrict the entry of pathogens
- innate non-specific immune defenses provide a rapid local response to pathogens after it has entered the body
- antigen-specific immune responses
the first line of defense (prevention)
- physical
skin- prevents entry (tight junctions, desmosomes, gap junctions)
mucous membrane- traps dirt and microbes - chemical
sweat- high levels of sodium kill certain types of bacteria
acidic environments- low pH
lysozyme- antibacterial enzymes inhibit cell wall formation
the second line of defense
- internal cellular
- chemical defense
defensive cells
phagocytes(neutrophils and macrophages)- eat foreign invaders
eosinophils- kills parasites
natural killer cells- degrade the structural integrity of cell wall (in the body)
defensive proteins
interferons- slows the spread of viral copes
complement system- stimulate histamine
inflammation
redness, heat, swelling, pain- increases blood flow, recruits defensive cells, promotes faster healing
fever
increase in temp- slows bacterial growth, speeds body defense
the third line of defense (adaptive immune response)
lymphocytes-
B-lymphocytes- generate diverse antibodies
T-lymphocytes- secretes chemical messengers
Plasma cell- secretes antibodies
adaptive immunity
- t-cell recognizes a foreign invader and records a copy of the antigen (memory t-cell)
- sends the copy to b-cells which activates it (effector t-cells)
- starts to produce a recipe for that antibody to fight the antigen (memory b-cells)
- records the recipe and b-cells send it to plasma cells and send the recipe throughout the body (effector b-cells)