Loratidine

Question 1

What is the MOA of Loratidine?

Answer 1

Loratidine is a non sedating antihistamine
It blocks (antagonises) peripheral histamine receptors - blocking the action of histamine and reducing itching and redness

Question 2

What are the indications for loratidine?

Answer 2

• minor allergic reactions confined to the skin

* prominent itch associated with anaphlaxis provided all systemic signs of anaphylaxis have resolved

Question 3

What are the contraindications and cautions for loratidine?

Answer 3

1. Known severe allergy to loratidine
2. Age less than one year
   Loratidine should only be given to pregnant women with caution (and should usually be withheld)

Question 4

What doseage of loratidine should be administered?

Answer 4

10mg for an adult or child over 12 years

5mg for a child aged 1-11 years