Liver abscess/cyst Flashcards

1
Q

What is the defintion of liver abscess/cyst?

A

collections of thick fluid (cyst) or pus (abscess) containing dead cells, pathogens +/- blood

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2
Q

When are Liver abscess/cysts more common?

A

diabetic patients

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3
Q

What are 4 types of liver asbcess/cyst?

A
  1. Pyogenic abscess
  2. Amoebic abscess
  3. Hydatid Cyst
  4. PCLD
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4
Q

What are signs and symptoms of liver abscess/cyst?

A
  1. Fever
  2. Malaise
  3. Weight loss / loss of appetite
  4. RUQ pain
  5. Jaundice
  6. Tender hepatomegaly
  7. Dullness to percuss (ascites)
  8. Hx of foreign travel
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5
Q

What are Ix for liver asbcess/cyst?

A
  1. Bloods
  2. Stool cultures
  3. Aspiration and culture of lesion
  4. Imaging: Liver USS, CT or MRI
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6
Q

What bloods are done?

A
  1. FBC
  2. CRP
  3. LFTs
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7
Q

What imaging is done?

A

Liver USS, CT or MRI

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8
Q

What is the management of bacterial source liver ascess/cyst?

A
  1. drainage plus long course antibiotics

2. amoxicillin + ciprofloxacin + metronidazole

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9
Q

What is the management of amoebic source liver ascess/cyst?

A

antibiotics targeting anaerobes i.e. metronidazole

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10
Q

What is the management of hyatid abscess liver ascess/cyst?

A
  1. sterilisation with anti-fungals
  2. i.e. mebendazole then surgical resection
  3. Percutaneous aspiration contraindicated
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11
Q

What is the cause of pyogenic asbcess?

A
  • S. Aureus (kids)

- E. Coli (adults)

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12
Q

What is a pyogenic abscess related to?

A

60% related to biliary disease e.g., gallstones, strictures

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13
Q

What would USS show in a pyogenic abscess?

A

fluid filled cavity with hyperechoic walls

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14
Q

What is the management of a pyogenic abscess?

A

drainage plus long course of antibiotics

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15
Q

What is the causative organism for an amoebic abscess?

A

Entamoeba histolytica

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16
Q

What is the symptoms for an amoebic abscess?

A

amoebic dysentery (profuse bloody diarrhoea)

17
Q

What does USS show for liver asbcess?

A

fluid filled structure with poorly defined boundaries

18
Q

What is the management of amoebic abscess?

A
  1. Aspiration = sterile, odourless fluid with pasty consistency
  2. Anaerobic antibiotics
19
Q

What is the causative organism for hydatid cyst?

A
  • Tapeworm Echinococcus granulosis infection

* Can be massive

20
Q

Where are hydatid cysts common?

A

Sheep-rearing countries

21
Q

What are hydatid cyst assoicated with?

A
  1. eosinophilia

2. abnormal LFTs

22
Q

What is the management for a hydatid cyst?

A

Antifungals and surgical resection

23
Q

What is polycystic liver disease associated with?

A
  • Usually in association with PCKD

* AD disorder