Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Z Year3 Gastro Conditions > Cholangiocarcinoma > Flashcards

Cholangiocarcinoma Flashcards

1
Q

What is cholangiocarcinoma?

A

cancers arising in the bile ducts either intrahepatic or extrahepatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are RF for cholangiocarcinoma?

A
  1. advancing age
  2. male
  3. smoking
  4. obesity
  5. chronic inflammation of bile ducts
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What may you see on the abdo exam for cholangiocarcinoma?

A

1 Virchow’s Node

2. Sister Mary Joseph nodule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the other symptoms of cholangiocarcinoma?

A
  1. FLAWS

2. RUQ pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are signs and symptoms of biliary obstruction (extrahepatic only)?

A
  1. Jaundice (painless)
  2. Palpable gallbladder
  3. Pruritus
  4. Pale stool, dark urine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What could chronic inflammation of the bile duct be due to?

A
  1. PSC
  2. cirrhosis
  3. bile duct stones
  4. infection – parasitic liver disease (Clonorchis sinensis liver fluke in SE Asia)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is sister mary joseph nodule?

A

periumbilical lymphadenopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is Virchow’s node?

A

supraclavicular lymphadenopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the gold standard investigation for cholangiocarcinoma?

A

ERCP with biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What bloods are done for cholagniocarcinoma?

A
  1. LFTs
  2. clotting studies
  3. CA19-9
  4. CEA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What other imagining is done for cholangiocarcinoma?

A
  1. Imaging – USS, MRCP

2. Radiography – PTC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the management for cholangiocarcinoma?

A
  1. Patients often present late which limits the scope for surgery
  2. Surgery
  3. Adjuvant chemotherapy or radiotherapy can prevent recurrence
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What type of surgery is available for cholangiocarcinoma?

A
  1. Removal of bile duct – small and localised tumour
  2. Partial hepatectomy – intrahepatic
  3. Whipple’s procedure – for distal bile duct tumours
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What would blood results show for cholangiocarinoma?

A
  1. raised ALP, GGT and BR

2. Prolonged PT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What does the USS allow?

A

identification of obstruction and dilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What does the MRCP show?

A

provides detailed images of the biliary system

17
Q

What does ERCP show?

A

invasive procedure allows biopsies to be taken whilst also providing a detailed view

18
Q

What is PTC?

A

percutaneous transhepatic cholangiography. Uses contrast and x-rays taken of the biliary system

19
Q

What can ERCP and PTC be used for?

A

therapeutic relief of obstructive symptoms via stent insertion

20
Q

What are DDx for cholangiocarcinoma?

A
  1. Biliary strictures

2. Cholangitis/Cholcystitis

21
Q

What are complications for cholangiocarcinoma?

A
  1. Biliary sepsis

2. Surgical risks

Z Year3 Gastro Conditions (48 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions