Liver Flashcards

1
Q

Center of hepatic lobule

A

Central venule

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2
Q

Portal triads located where, formed by what

A

Angles of hepatic lobules

Formed by three central venules

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3
Q

Components of portal triad

A

Branch of hepatic artery
Branch of portal vein
Bile duct

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4
Q

Hepatocyte function

A

Absorption of blood borne substances

Secretion of plasma proteins

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5
Q

Hepatic sinusoids lining

A

Fenestrated endothelial cells

Discontinuous basal lamina

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6
Q

Perisinusoidal cells located where, store what

A

Space of Disse

Store vitamin A

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7
Q

Perisinusoidal cells during cirrhosis

A

Transform into myofibroblasts

Produce collagen I

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8
Q

Subendothelial space of Disse

A

Between basal lamina and hepatocytes

Has interstitial fluid that drains into space of mall

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9
Q

Kupffer cells

A

Phagocytic, derived from monocytes

Line hepatic sinusoids

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10
Q

Canal of Hering (Cholangiole)

A

Receives bile from canaliculus

Carries bile to bile ductule

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11
Q

Spiral valve of Heister located where, formed by

A

Gallbladder

Mucosal folds

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12
Q

Rokitansky-Aschoff sinuses

A

Small diverticula of mucosa

May indicate pathological change

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13
Q

Major ducts, lined by what epithelium

A

Cystic duct
Hepatic duct
Common bile duct
Columnar epithelium

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14
Q

Bile produced/secreted by

A

Liver

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15
Q

Bile components

A

Bile acids
Water/electrolytes
Cholesterol/phospholipids
Bilirubin

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16
Q

Bilirubin produced from

A

Heme from hemoglobin of damaged RBCs

17
Q

Free bilirubin attaches to

A

Plasma albumin