Lecture 4: Epithelial Tissues Cell Membrane Flashcards
Cholesterol
Inner and outer leaflet
Phosphatidylcholine
Outer leaflet
Phosphatidylethanolamine
Inner and outer leaflet
Sphingomyelin
Outer leaflet
Glycolipid function
Create cell coat involved in cell-cell interactions and convey antigenicity
Glycosylphosphatidylinositol
Outer leaflet- important for cell signaling
Phosphatidylserine
Inner leaflet, negative charge
Phosphatidylinositol
Inner leaflet, negative charge, cell signaling
Lipid raft composition
Cholesterol, sphingolipids
Lipid rafts compartmentalize cellular processes by acting as organizing centers for:
Assembly of signaling molecules
Influencing membrane fluidity
Membrane protein trafficking
Regulating neurotransmission and receptor trafficking
Glycocalyx
Carbohydrate coat on extracellular surface that:
Protects cell from stress
Serves as barrier against microorganisms
Involved in cell-cell interactions
Glycolipid location in cell membrane
Outer leaflet with carbohydrate portion facing extracellular environment
Fluid mosaic cell membrane model
Developed by singer and nicolson
Model consists of a phospholipid bilayer forming thin oily fluid with associated proteins