Lecture 15: Nervous tissue Flashcards

1
Q

Telodendrites

A

Contain synaptic vessicles

Form presynaptic membrane

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2
Q

Multipolar neuron

A

Most common

One axon, multiple dendrites

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3
Q

Bipolar neuron

A

Have two processes, one at each end

Associated with special senses - olfactory/visual

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4
Q

Pseudounipolar

A

Have single process from body that bifurcates

Found in dorsal root ganglia

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5
Q

Golgi I neuron

A

Long axons which leave the gray matter

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6
Q

Golgi II

A

Short axons which ramify through gray matter

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7
Q

Epineurium

A

Covers entire nerve
Supplied by blood and lymphatics
Type I collagen and fibroblasts

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8
Q

Perineurium

A

Dense CT
Covers fascicles
Epithelial-like fibroblasts with tight junctions
Blood nerve barrier

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9
Q

Endoneurium

A

Thin layer of reticular CT
Surrounds individual fibers/schwann cells
Type III collagen

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10
Q

Presynaptic membrane contains

A

Dense bodies

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11
Q

SCa transport used by

SCb transport used by

A

Preassembled microtubules, neurofilaments

Enzymes, actin, clathrin

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12
Q

Intermediate transport used by

A

Mitochondria, other membrane bound organelles

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13
Q

Fast transport used by

A

Synaptic vessicles

Neurotransmitters

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14
Q

Glial cells derived from

A

Embryonic neural crest tissue

-except microglia

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15
Q

Astrocytes location/structure

A

Only in CNS

Numerous processes w/ expanded feet (pedicles) that terminate on capillaries or pia mater

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16
Q

Fibrous astrocytes

A

White matter

Long processes w/few branches

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17
Q

Protoplasmic astrocytes

A

Gray matter

Short processes w/many short branches

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18
Q

Astrocyte function

A

Regulate composition of intracellular environment
BBB- end feet form glia limitans
Development of cerebral cortex

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19
Q

Oligodendrocytes location/function

A

CNS only
Closely associated with neuron cell bodies, function as satellite cells
Surrounds axons in gray matter
Myelinate axons in CNS-each one myelinates several

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20
Q

Schwann cells

A

Myelinate single portion of axon in PNS

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21
Q

Microglial cells derived from/function

A

Derived from macrophage precursors
Phagocytic in CNS
Recruit leukocytes across BBB
Module immune response w/astrocytes

22
Q

Ependymal cells

A

Ciliated cuboidal
Function in transport
May secrete cerebrospinal fluid in choroid plexus

23
Q

Satellite cells

A

Form moons around cell bodies in ganglia

Insulators

24
Q

Internal and external mesaxon

A

Outer and innermost points of fusion between the outer leaflets

25
Q

Intraperiod line

A

Electron dense line created by extracellular space between outer leaflets

26
Q

Major protein zero

A

PNS-intraperiod lines- binds OUTER leaflets
Mutations are related to Charcot-Marie-Tooth diseases
In CNS this protein is replaced by proteolipid protein-mutations in it cause Pelizaeus-Merzbacher disease

27
Q

Major dense line

A

Line created by cytoplasmic space between inner leaflets

28
Q

Myelin basic protein

A

PNS-inner leaflets

Stabilized lipids

29
Q

Schmidt-Lanterman clefts

A

Residual areas of cytoplasm within major dense lines

30
Q

Astrocyte endfoot contacts the _______ in the _____

A

Node of ranvier in the CNS

31
Q

PNS- node of ranvier covered by

A

Schwann cell processes

32
Q

Connexin 32 expressed in ____ mutation causes ____

A

Schwann cells

Mutation causes Charlot-Marie-Tooth-disease

33
Q

SNAPs

A

Bind vesicles to presynaptic membrane

34
Q

Synapsins

A

Filaments in presynaptic membrane

35
Q

Meninges and spaces listed superficial-deep

A

Epidural space
Dura mater
Subdural space
Leptomeninx

36
Q

Dura mater “tough mother”

A

Thick sheet of dense fibrous CT
Found in cranial cavity and spinal cord
Receive blood from CSF

37
Q

Subarachnoid space

A

Between arachnoid and pia mater- filled by CSF

38
Q

Arachnoid villi

A

Allow CSF to flow from subarachnoid space into dural sinuses

39
Q

Pia mater is continuous with

A

Perivascular CT of cerebral/spinal cord blood vessels

40
Q

Pia mater tightly attached to

A

Nervous tissue of brain

41
Q

Perivascular space is covered by

A

Pia mater

42
Q

Choroid plexus cell type/cell linked by

A

Simple cuboidal cells

Tight junctions

43
Q

Choroid plexus capillaries formed by

A

Endothelial cells lacking tight junctions

44
Q

Choroid plexus and CSF

A

Na, K, ATPase pumps in apical membrane of choroid plexus pump fluid into lumen leading to CSF in ventricles

45
Q

Ependyma lines

A

Ventricular walls-simple cuboidal

46
Q

Ependymal cells linked by and in contact with

A

Zonula adherens

Contact astrocytic feet

47
Q

Dorsal root ganglia neurons are

A

Pseudopolar

48
Q

Dorsal root postganglionic axons are

A

Myelinated

49
Q

Satellite cells in dorsal root ganglia

A

Form layer around cell body of neuron

50
Q

Autonomic neuron type-recieve info from

A

Multipolar-recieve input from myelinated preganglionic neurons

51
Q

Autonomic postganglionic axons are

A

Not myelinated