Lecture 26: Digestive glands and liver

Question 1

Duct of Wirsung

Answer 1

Main excretory duct from pancreas

Question 2

Duct of Santorini

Answer 2

Smaller accessory duct from pancreas

Question 3

Interlobular ducts epithelium

Answer 3

Simple columnar

Question 4

Intercalated ducts epithelium/characteristics

Answer 4

Low cuboidal
Cells have receptors for secretin
Cells secrete water and bicarbonate

Question 5

Acinar cells

Answer 5

Pyramidal serous cells
Basal zone is basophilic and contains nucleus&RER
Apical zone with zymogen granules containing precursors of pancreatic enyzmes

Question 6

Centroacinar cells

Answer 6

Form truncated cuboidal epithelium within lumen of acini
Continuous w/epithelium of intercalated duct
Unique to pancreas

Question 7

What is the function of CCK

Answer 7

Causes release of digestive enzymes from serous acinar cells

Question 8

What is the function of secretin

Answer 8

Causes release of bicarbonate-rich, alkaline fluid from ductal epithelial cells

Question 9

Digestive enzymes (zymogens) stored where, synthesis/secretion controlled by what

Answer 9

Stored in vesicles in golgi
SS controlled by peptides secreted from duodenal enteroendocrine cells
Synthesized as inactive proenzymes on RER of acinar cells

Question 10

Bicarbonate ion secretion regulation

Answer 10

Bicarbonate is secreted by duodenal enteroendocrine cells when stimulated by food entering small intestine

Question 11

Synthesis of bicarbonate ion

Answer 11

Carbon dioxide diffuses into intercalated ducts from blood
Bicarbonate made w/help from carbonic anhydrase
It is actively transported to lumen of intercalated duct

Question 12

Islets of Langerhans

Answer 12

Endodermal derived cell aggregations which are interspersed irregularly among the acini

Question 13

Cell types of islets of langerhans

Answer 13

A-cells – presumed to form glucagon
B-cells – more numerous, produce insulin
D-cells – Secrete somatostatin- helps to control levels of insulin and glucagon