Lipoglycopeptides Flashcards
1
Q
Lipoglycopeptides prototype
A
Televancin (Black Box warning for pregnancy and lactation).
2
Q
Televancin indications
A
Treatment of complicated skin and skin-structure infections caused by susceptible bacteria.
3
Q
Televancin actions
A
Affects bacterial cell wall synthesis leading to disruption of cell membrane function and bacterial cell death.
4
Q
Televancin route, onset, peak
A
IV, rapid, end of infusion
5
Q
Televancin T 1/2
A
8 to 9.5 hours; site of metabolism unknown; excreted in the urine.
6
Q
Televancin adverse effects
A
Nausea, vomiting, diarrhea, taste alterations, QT prolongation, nephrotoxicity, foamy urine.
