Aminoglycosides Flashcards
0
Q
Gentamicin indications
A
Treatment of serious infections caused by susceptible bacteria.
1
Q
Aminoglycoside prototype
A
Gentamicin
2
Q
Gentamicin actions
A
Inhibits protein synthesis in susceptible strains of gram-negative bacteria, disrupting functional integrity of the cell membrane and causing cell death. (Inhibits protein synthesis by binding to ribosomes, leading to misreading of genetic code).
3
Q
Gentamicin Route, Onset, Peak
A
IM/IV, rapid, 30-90 min
4
Q
Gentamicin adverse effects
A
Sinusitis, dizziness, rash, fever, risk of nephrotoxicity.
