Flouroquinolones

Question 1

Flouroquinolones prototype

Answer 1

Ciprofloxacin

Question 2

Ciprofloxacin indications

Answer 2

Treatment of respiratory, dermatological, urinary tract, ear, eye, bone and joint infection; treatment after anthrax exposure, typhoid fever.

Question 3

Ciprofloxacin actions

Answer 3

Interferes with DNA replication in susceptible gram-negative bacteria, preventing cell reproduction.

Question 4

Ciprofloxacin route, onset, peak, duration

Answer 4

Oral, varies, 60-90 min, 4-5 h;

IV, 10 min, 30 min, 4-5 h

Question 5

Ciprofloxacin adverse effects

Answer 5

Headache, dizziness, hypotension, nausea, vomiting, diarrhea, fever, rash.