linfomi IIC Flashcards

1
Q

MCL

A

ki67 >30 aggressivo

slg
CD5
CD19
CD20
CD43
ciclina D1
SOX11

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2
Q

Hodgkin classico

A

CD30
CD15
marker b assenti o deboli
pax-5 debole
EBV marker LMP1 e EVER
CD45- BOB1-

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3
Q

Hodgkin nodulare a prev linfocitaria

A

CD45+
marcatori B: CD19, CD20, CD79a
BOB1, PU.1, PAX-5
CD15- CD30-
CD4+ CD57+ PD1+ (t helper)

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4
Q

Burkitt

A

Slg+
CD10
CD19
CD20
CD43 +/-
bcl-6 +++/-
IRF-MUM1 —/+

ki67 100%

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5
Q

DLBCL

A

ki-67% 22-55
slg +/-
CD19
CD20
CD22
CD23 +/-
CD79a
CD10++/-
CD5++/-
Bcl6
bcl2
c-myc
(se insieme double o triple hit)

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6
Q

FL

A

slg
CD10+/-
CD23+/-
CD19,20
CD43 -
Bcl6
IRF-MUM1 +/-

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7
Q

SMZL

A

Slg
CD19
CD20

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8
Q

LLC

A

slg
CD5
CD23
CD19,20
CD43
CD200
IRF-MUM1

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9
Q

hcL (Leucemia a cellule capellute)

A

CD19,CD20
CD22
CD11c, CD123, CD25
CD103
ci sono varianti con CD123 e CD15 neg

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