Lincosamides Flashcards
1
Q
What is the only linconsamide
A
clindamycin
2
Q
What is clindamycin’s MOA?
A
Inhibits protein synthesis by binding to 50S ribosomal subunit
3
Q
Clindamycin is very effective on this type of bacteria
A
anaerobes
4
Q
What types of infections can clindamycin treat?
A
Bone and joint, Gyn, intra abdominal, severe respiratory, anthrax, malaria, MRSA, clostridium
5
Q
Clindamycin is also known as ____ in a pill
A
diarrhea
6
Q
What 3 aerobes are resistant to clindamycin?
A
G+: enterococci faecalis
G-: N. meningitidis, enterobacteriaceae
7
Q
What other ADR’s does clindamycin have?
A
N/V, rash, jaundice, leukopenia
