limbic system

Question 1

what is the limbic system - location wise

Answer 1

ring of cortical components surround subcortical nuclei and connecting paths

Question 2

how old is the limbic system

Answer 2

Deepest part of the brain is the oldest part of the brain – this is where the limbic system is

Question 3

olfactory system and the limbic system

Answer 3

smell makes you remember something (poem)

The olfactory system has massive inputs to the limbic system

Question 4

Amygdala functions

Answer 4

in behavioral awareness and passion

(charge to drive)

Question 5

Hippocampus functions

Answer 5

memory formation and retrieval
connects to other brain regions for memory storage and recall
much through entorhinal cortex

Question 6

key thalamic nuclei with limbic connections

Answer 6

Mammillary body (of hypothalamus)

Anterior nucleus of thalamus

Medial dorsal nucleus of thalamus

Question 7

overall Limbic system connections

Answer 7

lots of talk, and still under construction

Question 8

Fornix limbic connection

Answer 8

from the mamillary body to the hippocampus (black)

Question 9

Mammillothalamic track

Answer 9

full memeory and learning - emotion and drive

mamillary bodies to the anterior nucleus of the thalamus

Question 10

Medial forebrain pathway

Answer 10

the major output pathway used by the post hypo and has pathways to the BS for the ANS and to the limbic system

Question 11

Cingulate bundle

Answer 11

communication from the cingulate cortex to all other areas of the cortex

The cingulate has a lot input to the cortex about weighting behavior

Question 12

Cingulate cortex functions

Answer 12

mood, thinking, moving and visual processing

these are all on different areas of the cortex

Question 13

Cingulate cortex connects with what

Answer 13

the rest of the cerbral cortex

Question 14

Motor sensory area of the cingulate cortex

Answer 14

role- making the decision to move

Question 15

what are motor skills

Answer 15

voluntary, goal-directed, sequences of motor actions

Question 16

limbic​ activity in preparation of a skilled movement

Answer 16

activity goes down

If you really know how to do a movement – you do not think a lot about it/decide to do it

when people become experts in their motor skill the activity become automatic

Question 17

Papez circuit - function

Answer 17

important​ for episodic memory consolidation - Establishing the emotion sig of memory for survival

Question 18

hypo role in papez circuit

Answer 18

The hypo has actions to change the phys of the body through the ANS - this change is seen because​ of emotion expressed

Question 19

fornix - papez circuit

Answer 19

major pathway for processing cognition to emotions

Question 20

Mammillo-thalamic tract - papez

Answer 20

• Emotion and physiology became conscious aware – I am aware of how I am feeling

Question 21

Prefrontal path - papez

Answer 21

major pathway into the hippo, for memory info
emotional based learning
entrohinal cortex

Question 22

Hypothalamus and brainstem nuclei do what for the limbic system

Answer 22

carry out the roles of weight decisions

Question 23

Limbic function in BG loop

Answer 23

amygdala, hippocampus

Most of the input is to the ventral striatum (red arrows)

this is intergrateing limbic function with regulation of motivation, reward-based action and mood

Question 24

Modulator in the limbic BG loop

Answer 24

ventral tegmental area (dope input to the striatum)

Dope driving the selection and energizing it

Question 25

what is the ventral sriatum.

Answer 25

nucleus accumbens

Question 26

would limbic drive for BG bee seen in early learning

Answer 26

no - this is based or reward therefore we need to know how to do the action before this

Question 27

Goal directed behavior

Answer 27

something you expect to accomplish our have reward for which mean we know how to do something and know how to respond

Question 28

what is role of the The ventral striatum in the limbic BG path

Answer 28

integrates the limbic drive and cortical planning to facilitate goal directed behavior

Question 29

what does the hippo do to the VS

Answer 29

Depolarizes neurons in the VS

Question 30

high limbic drive leads to what

Answer 30

If the limbic drive it high – this leads to a quick strong well learned response – do it

Question 31

Ventral tegmental area role

Answer 31

Dope input: regulating the balance between limbic drive and prefrontal cortex drive

Question 32

what does ventral tegmental input allow you do to in the limbic​ BG

Answer 32

This allows who to shift your drive from an emotional quick action (limbic driven) to having the flexibility to choose a response strategy

Question 33

the Prefrontal cortex drive allows for what kind of response

Answer 33

flexibility to choose the response strategy

Question 34

in Schizophrenia what circuit is interrupted​

Answer 34

hippocampal -PFC-Nuc Accumbens circuit and dopamine modulation disrupted

Question 35

hippocampal -PFC-Nuc Accumbens circuit and dopamine modulation disrupted circuit interruption​ leads to what

Answer 35

lose cognitive flexibility difficulty with switching responses in executive functions

Question 36

when seeking or expecting​ reward - VTA dopaminergic input facilitates BLANK via what receptors

Answer 36

limbic drive D1 receptors

Question 37

VTA inputs when reward expectation is removed

Answer 37

D1 receptor firing is suppressed allows PFC inputs to dominate, thus flexibility in behavioral response.

Question 38

PFC deficits seen with Schizophrenia due to

Answer 38

D1 receptor activation - increased hippocampal input to Nuc Accumbens (limbic drive) facilitates dopamine release from VTA input, attenuates PFC effects