Lifespan Flashcards
Gerontology
Study of normal aging process
Geriatrics
Branch of medicine concerned with the illnesses of old age
Categories of elderly
Young elderly_____
Old elderly_____
Old, old elderly
YE: 65-74 yo
OE: 75-84 yo
OOE: 85+
Leading causes of death in elderly (in order)
CHD (31%) CA (20%) CVD COPD Pneumonia/flu
Leading causes of disability in elderly
Arthritis (49%)
HTN (37%)
Hearing impairment (32%)
Heart impairment (30%)
Genetic theory of aging
Aging is intrinsic.
No one gene is responsible
Premature aging syndromes are examples of faulty genetic programming
Hutchinson-Gilford Syndrome
Progeria (premature aging) in childhood
Werner’s Syndrome
Progeria of young adults
Doubling/biological clock theory of aging
Hayflick’s limit theory
Limited number of genetically planned cell replications
Free radical theory of aging
Free radicals damage cell membrane and DNA.
results in decreased O2 delivery and tissue death
Can lead to atherosclerosis, cell mutation, CA
Cell mutation theory of aging
errors in synthesis of DNA/RNA lead to aging changes
Hormonal theory of aging
Impaired hormonal functions lead to aging
Which 3 glands have the biggest impact on aging
Hypothalamus, pituitary, adrenal
Thyroxine (T4)
master hormone of the body.
controls protein synthesis
Increase of ______ hormones can damage the brain, including the memory center, the _____
stress (cortisol)
Hippocampus
Immune cells also affected
Immunity theory of aging
thymus size decreases, bone marrow efficiency decreases
These lead to impaired immune response
Environmental theory of aging
Aging is caused by accumulation of toxins such as UV light, saturated fats, heavy metals, etc
Impairs DNA synthesis
In the elderly, there is a selective loss of type (I/II) fibers
II
this leads to an increased proportion of type I (slow twtich) fibers, limiting power
Aging’s effect on collagen
Denser
More irregular
Lower water content
Lower elasticity
Can strength training positively impact older adults strength levels and fitness
You betcha
Which has been shown to produce quicker results in the elderly, moderate intensity or high intensity
High intensity (70-80% 1RM)
Common postural changes in the elderly
Forward head kyphotic T spine
Flat lumbar spine
hip/knee flexion contractures
What are lipofuscins?
finely granular yellow-brown pigment granules composed of lipid-containing residues of lysosomal digestion
increase with aging, and can cause detrimental aging effects
Age-related tremors (essential tremors)
Often in hands, head, or voice
Benign and slowly progressive
Often postural or kinetic
Rarely resting
Presbyopia
Age related visual loss
poor focus and blurry images
Due to loss of accomodation and decreased elasticity of lens
Cataracts
Opaque lens due to change in proteins
Central vision loss first
Glaucoma
Increased intraocular pressure, degneration of optic disc
loss of peripheral vision first, can progress to total blindness
Macular degeneration
loss of central vision
may progress to total blindness, or pt may retain peripheral vision
Diabetic retinopathy
Damage to retinal capillaries
Central vision impairment, complete blindness rare
Homonymous Hemianopsia
loss of half of visual field of each eye
cannot see one total half of the visual field (R/L)
Conductive hearing loss
mechanical
Damage to middle ear ossicles or exterior structures
All frequencies affected
Tinnitus may be present
Sensorineural hearing loss
Central/neural
Meniere’s disease
Episodic attacks of tinnitus and dizziness (pt may feel pressure in ears)
sensorineural hearing loss possible
BPPV
Brief episodes (less than 1 min) associated with position change
Terminal drop
The most significant loss of cognitive function, generally occurs in years immediately proceeding death
Aging effects on pulmonary function
Decreased total lung capacity
Increased residual volume
Decreased vital capacity
Osteoporosis
BMD at hip/spine that is 2.5 SD or more below mean
Osteopenia
BMD at hip/spine that is 1-2.5 SD below mean
Diseases impacting bone health
Hyperthyroid DM Hyperparathyroid SLE Celiac disease gastric bypass pancreatic disease MM sickle cell ESRD Paget's CA
Medications affecting bone loss
Corticosteroids Chemo Thyroid hormone estrogen antagonists anticonvulsents
Risk factors for low BMD
Family history White/Asian Early menopause Smoking Small frame
Common locations of osteoporotic fx’s
Vertebrae
Femoral neck
Radius
Humerus
Medicine options for low BMD
Bisphosphonates
Calcitonin
Estrogens
Calcium and Vitamin D recommendations
Ages of 50:
Calcium: 1200 mg
Vit D: 800-1000 IU
Verbal ability peaks at____ but is well maintained until____
30, 60’s
Numeric abilities peak _____ and are well maintained till _____
mid 40’s, 60’s
Intellect changes do not typically show until___. but declines are not significant in every day life until____
60’s, 80’s
Interventions for low BMD
weight bearing exercises postural corrections functional balance tai chi gait training education-fall risk, fracture prevention