lesson 7 regulation of gene expression Flashcards
what is gene regulation
gene regulation determines whether a gene is active or not
determiens the level of activity and the amount of protein available in teh cell
what are constitutive genes
housekeeping genes that are always active because the proteins are neede dfor survival of the cell.
genes that code for dna repair and cell cycle regulation
what are the three levels of control in prokaryotes
can occur during:
transcription
translation
and after a protein ahs been synthesized
what is the operon
operon is the most common regulation during initiation of transcription
- in prokaryotes, genes are clustered in a region under the control of a single promotor. this is called an operon which is a cluster of genes goruped together under the control of one promotor
- one mRNA called a polycisronic mRNA is synthesized for multipe genes in the same metabolic pathway
what is the lac operon
the genes that encode the enzymes needed to break dow nthe sugar lactose are found in the lac operon on the e.coli chromosome.
- the lac operon contains the coding region containing genes for three enymes tha t break down lactose and the regulator region
what is the regulatory region components
the promotor which involves the transcription of the alctose metabolizing enzymes
the operator which is a dna sequence to which a protein/ a repressor binds to inhibit transcription initation
and the cap binding site which is a dna seuence to which cap binds to increase the rate of transcription