Lesson 18: Rhabdoviridae

Question 1

Rhabdoviridae is included with the families

Answer 1

Bornaviridae, Filoviridae,
Pneumoviridae, and Paramyxoviridae in the order Mononegavirales

Question 2

Rabies
 Etiology:

Answer 2

Lyssavirus

Question 3

Rabies
 Etiology: Lyssavirus
 _________, causes fatal encephalomyelitis in humans and other mammals
 Zoonotic, considered as Risk Group III pathogen (high individual risk, low
community risk, with treatment)
 Rare cases of human-to-human transmission (due to infected organ
transplantation)

Answer 3

Neurotropic

Question 4

Rabies
2 types of transmission

Answer 4

Sylvatic cycle: or jungle cycle, wildlife transmission
 Urban cycle: transmission occurs between domestic dogs,
monkey cats, human

Question 5

Rabies, The virus moves by ___________ before demonstrating centrifugal moveme

Answer 5

centripetal movement

Question 6

: virus moves from site of wound (muscle)
to the peripheral nervous system to the central nervous system
(gray matter)

Answer 6

Centripetal movement

Question 7

once the CNS are affected, the virus
presents into the salivary gland

Answer 7

Centrifugal movement:

Question 8

Babies
Incubation period : 14 - 90 days, depends upon;
(1) site of bite - farther from head (longer incubation period)
or in fingers (shorter incubation period due to numerous
peripheral nerves in extremities)
(2) No. Of bite
(3) load of virus (more viral load - shorter incubation period)