Lesson 16: Flaviviridae

Question 1

Most viruses in the genus Flavivirus are transmitted by ____ and
cause encephalitis

Answer 1

arthropods

Question 2

cause bovine
viral diarrhoea, border disease and classical swine fever (hog cholera)

Answer 2

Pestivirus

Question 3

Causes inapparent infection, acute disease
(bovine viral diarrhoea) and sporadic fatal
infection (mucosal disease).
Infection of pregnant animals may result in
abortion, congenital defects or persistent
infection (immunotolerance)

Answer 3

Bovine viral
diarrhoea virus 1
and 2

Question 4

Important infection of pregnant ewes and
cause of abortion or congenital abnormalities
(hairy shaker lambs)

Answer 4

Border disease virus

Question 5

Economically significant disease.
Highly contagious, generalized infection that
is frequently fatal.
Nervous signs, abortion and congenital
tremor are features of the disease

Answer 5

Classical swine
fever (hog cholera)
virus

Question 6

Economically significant disease.
Highly contagious, generalized infection that
is frequently fatal.
Nervous signs, abortion and congenital
tremor are features of the disease

Answer 6

Classical swine
fever (hog cholera)
virus

Question 7

Louping ill virus
Present in specific regions of ___.
Transmitted by the ________.
Produces encephalitis in sheep

Answer 7

Europe
tick Ixodes ricinus

Question 8

Water birds are reservoir
host.
Infection in pigs is associated with abortion
and neonatal mortality.
May cause nervous disease in horses

Answer 8

Japanese
encephalitis

Question 9

Transmitted by mosquitoes; birds are the
natural hosts. Sporadic cause of serious CNS
disease in humans and horses

Answer 9

Wesselsbron virus

Question 10

Outbreaks of progressive paresis and
paralysis in turkeys in Israel and South
Africa. Mosquito-borne virus

Answer 10

Israel turkey
meningoencephalitis
virus

Question 11

 Infection with bovine viral diarrhoea virus (BVDV) is common in cattle
populations worldwide
 The virus is responsible for acute disease (bovine viral diarrhoea) and a chronic
syndrome associated with persistent infection (mucosal disease).
 Isolates of BVDV can be segregated into two genotypes now considered
separate species, BVDV 1 (classical BVDV isolates) and BVDV 2 (atypical BVDV
isolates).

Question 12

is a very contagious and frequently fatal disease of pigs.

Answer 12

Classical swine fever( Hog Cholera)

Question 13

are the only natural hosts of CSFV and direct contact
between

Answer 13

Pigs and wild boar

Question 14

CLASSICAL SWINE FEVER OR HOG CHOLERA
Pigs are usually infected by the ______ and the ______ is the primary
site for viral multiplication. The virus spreads to the draining regional lymph
nodes before entering the bloodstream.

Answer 14

oronasal route
tonsil

Question 15

Classical swine fever or hog cholera
Degeneration of endothelial cells in conjunction with a severe thrombocytopenia
is responsible for the __________. Petechiae on
the surface of the kidneys and in the lymph nodes are the most consistent
findings. Splenic infarction, if present, is considered highly characteristic of acute
swine fever

Answer 15

multiple haemorrhages seen in acute CSF

Question 16

Classical swine fever or hog cholera
The principal CNS lesion is

Answer 16

perivascular cuffing