Lepto and other Kidney Infections Flashcards
bacteria that commonly cause urinary tract infections of the bladder
- Enterobacterales
- staphylococcus pseudintermedius
- Beta hemolytic Streps and Enterococci
- Pseudomonas aeruginosa
bacteria that commonly cause UTI infections of the kidney
lepto
leptospira are gram __ and __
negative, strict aerobes
the _ of the renal tubules is the natural reservoir for leptospira
lumen
Lepto can survive in the environment for __ months and like __ areas with __pH and __ climate
6 months, moist, alkaline, mild
what are 3 sources of lepto?
- urine of carrier animals
- body secretions of animals with disease (milk, urine, placenta)
- spread directly or indirectly through environment
common routes of infection for lepto are ___ and __
skin wounds/abrasions and splashing of organism into eye or mucus membranes
systemic disease by lepto
invades through the mucous membranes or broken skin and invades multiple parenchymatous organs causing inflammation and vasculitis
repro tract disease by lepto
venereal transmission also occurs with ascending infections
outcomes of lepto infection
- dz or death
- abortion
- carrier state (in kidneys )
- infection cleared
T/F: host preference may vary between geographic regions over time
T
Host-adapted susceptibility
infects hosts easily and are endemic causing mild and chronic disease persistently in the kidneys. vaccines ineffective
Incidental hosts/infections:
low host susceptibility but high pathogenicity with acute and severe disease that have a short renal phase. vaccines better
what 4 serovars are in the lepto vaccine
grippotyphosa
pomona
canicola
icterohemorrhagiae
clinical signs of acute form of lepto
renal: pu/pd, oliguria, anuria
hepatic: icterus
Bleeding tendencies: direct vascular damage-> hematuria, hematochezia, melena, epistaxis, petechiae
tachypnea/dyspnea
lepto clin path
CBC: anemia, neutrophilia, lymphopenia, thrombocytopenia
Chem: hypoalbuminemia, azotemia, increased ALT, ALP, hyperbilirubinemia
T/F: cats rarely get clinical disease with lepto
T
Lepto in cattle
host adapted: abortion, venereal transmission
incidental serovars: fever, anemia, jaundice, agalactia, abortion
lepto in swine
host adapted: mild/subclinical
incidental: abortion and nephritis
lepto in horses
host adapted: abortion, infertility
incidental: abortion, equine recurrent uveitis, systemic dz
2 main ways we dx lepto
PCR
serology- in clinic tests and send outs (MAT)
Tx of lepto
supportive care
antimicrobial therapy - doxycyline
vx is effective for 12 months in dogs
corynebacterium renal is infectious __ that is a disease of __ that causes __ infections
pyleonephritis, cows (females), ascending
actinobaculum suis is another infectious pyelonrphritis but it causes dz in __ while boars are __ and is an __
sows, carriers, obligate anaerobe
