Lepto and other Kidney Infections Flashcards

1
Q

bacteria that commonly cause urinary tract infections of the bladder

A
  • Enterobacterales
  • staphylococcus pseudintermedius
  • Beta hemolytic Streps and Enterococci
  • Pseudomonas aeruginosa
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2
Q

bacteria that commonly cause UTI infections of the kidney

A

lepto

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3
Q

leptospira are gram __ and __

A

negative, strict aerobes

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4
Q

the _ of the renal tubules is the natural reservoir for leptospira

A

lumen

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5
Q

Lepto can survive in the environment for __ months and like __ areas with __pH and __ climate

A

6 months, moist, alkaline, mild

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6
Q

what are 3 sources of lepto?

A
  1. urine of carrier animals
  2. body secretions of animals with disease (milk, urine, placenta)
  3. spread directly or indirectly through environment
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7
Q

common routes of infection for lepto are ___ and __

A

skin wounds/abrasions and splashing of organism into eye or mucus membranes

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8
Q

systemic disease by lepto

A

invades through the mucous membranes or broken skin and invades multiple parenchymatous organs causing inflammation and vasculitis

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9
Q

repro tract disease by lepto

A

venereal transmission also occurs with ascending infections

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10
Q

outcomes of lepto infection

A
  1. dz or death
  2. abortion
  3. carrier state (in kidneys )
  4. infection cleared
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11
Q

T/F: host preference may vary between geographic regions over time

A

T

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12
Q

Host-adapted susceptibility

A

infects hosts easily and are endemic causing mild and chronic disease persistently in the kidneys. vaccines ineffective

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13
Q

Incidental hosts/infections:

A

low host susceptibility but high pathogenicity with acute and severe disease that have a short renal phase. vaccines better

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14
Q

what 4 serovars are in the lepto vaccine

A

grippotyphosa
pomona
canicola
icterohemorrhagiae

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15
Q

clinical signs of acute form of lepto

A

renal: pu/pd, oliguria, anuria

hepatic: icterus

Bleeding tendencies: direct vascular damage-> hematuria, hematochezia, melena, epistaxis, petechiae

tachypnea/dyspnea

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16
Q

lepto clin path

A

CBC: anemia, neutrophilia, lymphopenia, thrombocytopenia

Chem: hypoalbuminemia, azotemia, increased ALT, ALP, hyperbilirubinemia

17
Q

T/F: cats rarely get clinical disease with lepto

A

T

18
Q

Lepto in cattle

A

host adapted: abortion, venereal transmission

incidental serovars: fever, anemia, jaundice, agalactia, abortion

19
Q

lepto in swine

A

host adapted: mild/subclinical

incidental: abortion and nephritis

20
Q

lepto in horses

A

host adapted: abortion, infertility

incidental: abortion, equine recurrent uveitis, systemic dz

21
Q

2 main ways we dx lepto

A

PCR
serology- in clinic tests and send outs (MAT)

22
Q

Tx of lepto

A

supportive care
antimicrobial therapy - doxycyline

vx is effective for 12 months in dogs

23
Q

corynebacterium renal is infectious __ that is a disease of __ that causes __ infections

A

pyleonephritis, cows (females), ascending

24
Q

actinobaculum suis is another infectious pyelonrphritis but it causes dz in __ while boars are __ and is an __

A

sows, carriers, obligate anaerobe