Canine Hypothyroidism Flashcards
what are the most common etiologies of hypothyroidism?
- primary hypothyroidism is >95% of cases
- lymphocytic thyroiditis in 50% of cases
- idiopathic atrophy in 50% of cases
signalment of dogs with hypothyroidism
middle aged (5-7yrs old)
purebred dogs
clinical signs of hypothyroidism
- lethargy
- weakness: decreased metabolic rate and myopathy
- obesity
- exercise intolerance
- alopecia
- seborrhea
- myxedema
cardiovascular findings on dogs with hypothyroidism
- bradycardia
- weak pulses
- muffled heart sounds
- low voltage ECG complexes
- reduced myocardial contractility
T/F: hypocalcemia can cause localized or generalized peripheral neuropathies
T
what cns abnormalities are common with hypothyroidism?
multifocal CNS signs, hemiparesis, central vestibular signs, cerebellar, multiple cranial nerve deficits
reproductive abnormalities associated with hypothyroidism in dogs
severe cases for females may result in infertility, increased periparturient pup mortality and low birth weight
congenital hypothyroidism is more common in __ and common signs are __, __ and ___
cats, dwarfism, constipated, dull
how will hypothyroidism shown up on routine bloodwork
hypercholesterolemia with a mild non-regenerative anemia
in hypothyroidism the T4 should be __ but may be increased by __
increased, T4 autoantibodies
decreased thyroid hormones __ TSH
increases
primary hypothyroidism causes __ TSH
elevated
serum TSH is is elevated in what percent of dogs with hypothyroidism? what may be combined with this for dx?
65-75% of hypothyroid dogs, combined with T4 or fT4 is dx
what breeds have lower T4 and fT4 than other breeds?
sighthounnds
which thyroid hormone is least effected by non-thyroidal illness and autoantibodies?
fT4
