Lecture 9 - reproductive system development Flashcards
from which embryological germ layer is the reproductive system derived
intermediate mesoderm
the intermediate mesoderm swells to form the
urogenital ridge
urogenital ridge differentiates into
genital ridge and nephrogenic cord/ridge
outline the migratory oath that the primordial germ cells take to reach the genital (gonadal) ridges
wall of yolk sac > dorsal mesentery > gonadal ridge
which week does the primordial germ cells reach the gonadal ridge
6-7 week
genetic sex of an individual determined at
fertilization
gonad development begins with a __ stage
indifferent stage
gonads do not begin to acquire specific morphological characteristics (male/female) until the __ week
7th week
what are the two ducts shared by male/female genital systems during indifferent phase
mesonephric (Wolffian) duct and paramesonephric (Mullerian) duct
if embryo genetically male, primordial germ cells carry __ chromosome complex
XY
Y chromosome house __ gene which encodes for tests-determining factor (TDF)
SRY
the testis cords are composed of what two components
primitive germ cells and sertoli cells (sustentacular cells)
sertoli cells produce what hormone
anti-mullerian hormone or mullerian inhibiting substance
which hormone inhibits female genital ducts from forming
anti-mullerian hormone
__ cells lie in between testis cords and produce testosterone
Leydig cells
in male, most of __ duct persists, forming main genital ducts
mesonephric (wolffian) duct
testosterone, produced by Leydig cells, stimulates __ to develop
genital ducts
paramesonephric (mullerian) ducts degenerate under the influence of
AMH/MIS (anti-mullerian hormone)
the testes develop __ in the abdomen
retroperitoneally
which abdominal muscle does NOT contribute a layer covering the testis
transversus abdominis m.
as the testis descends through inguinal ring, it gets covered by
processus vaginalis
- visceral and parietal layer of tunica vaginalis
transversalis fascia (internal spermatic fascia)
internal abdominal oblique muscle (cremasteric fascia and muscle)
external oblique muscle (external spermatic fascia
as the testis descends through inguinal ring, it gets covered by ___,visceral and parietal layer of tunica vaginalis
processus vaginalis
as the testis descends through inguinal ring, it gets covered by ___, internal spermatic fascia
transveralis fascia
as the testis descends through inguinal ring, it gets covered by ___, cremasteric fascia and muscle
internal abdominal oblique m.
as the testis descends through inguinal ring, it gets covered by ___, external spermatic fascia
external abdominal oblique muscle
the surface epithelium in the developing ovary gives rise to second generation of cords known as the ___ cords
cortical cords
eipthelial cells surrounding an oogonium are called
follicular cells
oogonium + follicular cells =
primordial follicle
which duct persists in the female
paramesonephric duct or Mullerian duct
in the presence of estrogen and absence of testosterone and AMH, which ducts develop and which degenerate
paramesonephric (mullerian) ducts develop
mesonephric ducts degenerate
paramesonephric ducts develop into
main female genital ducts
-uterine tube
uterine canal
where does lower portion of vagina arise from
urogenital sinus
paramesonephric ducts give rise to uterine tube and uterine canal, the uterine canal then forms into __,__,__
corpus of uterus
cervix
upper portion of vagina
upper portion of vagina derived from uterine canal which is ___ germ layer
mesoderm
lower portion of vagina derived from urogenital sinus which is __ germ layer
endoderm
during 3rd week, mesenchymal cells from primitive streak migrate around cloacal membrane to form __ folds.
crainal to cloacal membrane, folds unit to form __
caudally, folds subdivide into __ and __
cloacal folds
genital tubercle
urethral folds and anal fold
female, the elevations on each side of the urethral folds are the
genital swellings
the elevations on each side of the urethra folds are the genital swellings, this will become ___(male) or ___(female)
scrotal swelling in male
labia majora in female
do the urethral folds fuse or nah in the male
do fuse
(male)end of 3rd month, the two urethral folds close over urethral plate forming
penile urethra
in the female, genital tubercle elongates only slightly forming __
clitoris
the urethral folds do not fuse in female, but develop into the
labia minora
