Lecture 9 Flashcards
What are adult stem cells? What are the properties?
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How were the first adult cells identified? Which ones? What experiment was done? What did this show?
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What are Haematopoietic stem cells? What are the properties? What is the niche?
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What are the properties of mesenchymal stem cells?
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What are the two populations of stem cells in the bone marrow? How are they used differently for treatment?
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What is the link in the niche of the two populations of the stem cells of the bone marrow?
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What are the different division patterns for tissue homeostasis? What method is preferred? Why?
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What is the role of TA cells in the gut? What do they form?
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What ways can cancer arise? Where can the mutation form?
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What is an example of cancer in the intestine? Where does the mutation occur? What is a consequence of this?
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How do you detect stem cell in mouse?
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What are the stem cells in the hair follicles?
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How to detect stem cells in humans?
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What was the experiment done to show the differentiating capability of stem cells?
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What is LacZ? What is it used for?
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What did the experiment show that bulge stem cells were? How?
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What is a stem cell niche? What are the properties?
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What are examples of stem cells and their niche’s?
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What is a consequence of the properties of the stem cells and niche of the intestine?
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How can systemic influence stem cells? What is an example?
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What is the aging of stem cells?
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What was the experiment which showed the systemic influence on stem cells?
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What is the relationship between number of divisions and risk of developing mutations? What is a consequence of this?
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What type of cells are there the most turnover generally? What is a consequence of this?
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How much do hereditary and environmental conditions play a role in cancer? However what shows that the turnover factor has a more significant role?
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