Lecture 9 Flashcards
Heart
Muscular double pump
Conical structure with apex to the left of the midline
Two functions of heart
- Pulmonary circuit
2. Systemic circuit
Pulmonary circuit
Right side receives oxygen-poor blood from the body and pumps it to the lungs
Systemic circuit
Left side receives oxygenated blood from the lungs and pumps through the body
Superior vena cava
Brings blood from upper half of body
Inferior vena cava
Brings blood from lower half of body
Divided at diaphragm
Bicuspid/mitral valve
Left AV valve
Tricuspid valve
Right AV valve
Mitral regurgitation
Blood flows back from left ventricle to left atrium
Aortic semilunar valve
Blood exits left ventricle
Pulmonary semilunar vlave
Blood exits right ventricle
Mediastinum
Surrounds heart
Pericardial cavity
Contains heart
Pericardium (2)
- Fibrous pericardium
2. Serous pericardium
Fibrous pericardium
Strong layer of dense connective tissue
Serous pericardium
Formed from parietal and visceral layers
Layers of heart wall (3)
- Epicardium
- Myocardium
- Endocardium
Epicardium
Visceral layer of serous pericardium
Myocardium
Consists of cardiac muscle arranged in circular and spiral patterns
Endocardium
Endothelium resting on a layer of connective tissue
Lines internal walls of heart
Atria
Receive blood from the pulmonary and systemic circuits
Ventricles
Pumping chambers of the heart
Internal heart divisions (2)
- Inter-ventricular septa
2. Inter-atrial septa
External heart markings (3)
- Coronary sulcus
- Anterior inter-ventricular sulcus
- Posterior inter-ventricular sulcus
Right atrium
Receives oxygen-poor blood from systemic circuit
Pentinate muscles give it ridges
Fossa ovalis
Tricuspid valve connects it to ventricle
Fossa ovalis
Depression in right inter-atrial septum
Remnant of foramen ovale
Right ventricle
Receives blood from right atrium through right AV valve (tricuspid valve)
Pumps blood into pulmonary circuit
Trabeculae carnae: elevations in ventricle like pectinate muscles
Papillary muscles open valves
Trabeculae carnae
Elevations in the ventricle, similar to pectinate muscles
Papillary muscles
Larger, prominent trabeculae, makes cusps move
Connected to tricuspid valve by chordae tendineae
Chordae tendineae
Cord-like tendons that connect the papillary muscles to the tricuspid valve and mitral valve in the heart
Pulmonary semilunar valve
Located at opening of right ventricle and pulmonary trunk
Left atrium
Makes up hearts posterior surface
Receives oxygen-rich blood from lungs through pulmonary veins
Opens into the left ventricle via bicuspid valve
Left ventricle
Forms apex of heart
Contains trabeculae carnae, papillary muscles, and chordae tenineae
Heart valves
Each composed of endocardium with connective tissue core
Lub (of lub-dup)
AV valves closing
Dub (of lub-dup)
Semilunar valves closing
Cardiac muscle tissue
Forms myocardium
Contracts by sliding filament mechanism
Cardiac muscle cells
Short and branching
One or two nuceli
Joined at intercalated discs
Two types of cell junctions: fasciae adherens and gap junctions
Intercalated discs
Complex junction to form cellular networks
Fasciae adherens
Desmosome-like junctions
Vagus nerve
Parasympathetic fibers that decrease heart rate
Cervical sympathetic chain
Sympathetic nerves that increase heart rate and strength of contraction
Coronary arteries
Arise from base of aorta
Left and right
Left coronary artery
AKA anterior inter-ventricular artery or left anterior descending artery
Right coronary artery
AKA posterior inter-ventricular artery or posterior descending artery
Coronary artery disease
Atherosclerosis, angina pectoris, myocardial infarction, silent ischemia, arrhythmias, congest cardiac failure
Atherosclerosis
Fatty deposits inside lumen of blood vessels
Angina pectoris
Chest pain
Myocardial infarction
Blocked coronary artery, heart attack
Coronary artery bypass graft
Bypass block to allow blood flow to where it needs to go
Congenital heart defects
Traced to 2 months of development
Most common defect is ventricular septal defect
Two categories:
1. Inadequately oxygenated blood reaches body tissues
2. Ventricles labor under increased workload