Lecture 2 Flashcards
Tissues
A group of closely associated cells that perform related function and are similar in structure
Most organs contain 4 tissue types
Epithelial tissue
Covers body surface or lines body cavity Forms parts of most glands Minimal extracellular material Specialized contacts between cells Avascular but innervated Receives nutrients from underlying connective tissue Quickly regenerates
Connective tissue
Support Connects other tissues together Mostly right under epithelium Most diverse and abundant tissue Few cells, abundant cellular matrix Common embryonic origin is mesenchyme
Muscle tissue
Movement, contractility
Nervous tissue
Control, excitability
Functions of epithelia
Protection Secretion Absorption Diffusion Filtration Sensory reception
Simple epithelia
Single layer of cells attached to basement membrane
Stratified epithelia
Multiple layers of cells
Squamous
Cells are wider than tall: plate like
Cuboidal
Cells are as wide as they are tall
Columnar
Cells are taller than they are wide
Simple squamous epithelium
Diffusion and filtration
Secretes lubricating substances in serosae
Located in renal corpuscles, alveoli of lungs, lining of heart, blood and lymphatic vessels (body cavities)
Simple cuboidal epithelium
Secretion and absorption
Located in kidney tubules, secretory portions of small glands, ovary surface
Stratified squamous epithelium
Adapted for protection from abrasion
Deeper layers of cells appear cuboidal or columnar
Thickest epithelial tissue
Regenerates from below
Named according to shape of cells at apical layer
Stratified cuboidal epithelium
Generally two layers of cube-shaped cells
Protection
Located at ducts of mammary glands, salivary glands and largest sweat glands
Basement membrane and diabetes
Basement membrane can become thick
Due to increase amounts of glucose binding to proteins of BM: glycosylation, especially in eye or kidney
Simple columnar epithelium
May contain goblet cells
Absorption, secretion of mucus, enzymes, etc
Ciliated types propel mucus or reproductive cells by ciliary action
Location of non-ciliated simple columnar epithelium
Lines digestive tract, gallbladder, ducts of some glands
Location of ciliated simple columnar epithelium
Lines small bronchi, uterine tubes and uterus
Pseudostratified columnar epithelium
All cell originate at basement membrane Only tall cells reach apical surface May contain goblet cells and bear cilia Nuclei lie at varying heights within cells, giving impression of stratification Secrete mucus and propel mucus by cilia
Location of non-ciliated pseudostratified columnar epithelium
Ducts of male reproductive tubes
Ducts of large glands
Location of ciliated pseudostratified columnar epithelium
Lines trachea and most of upper respiratory tract
Goblet cell
Unicellular exocrine gland
Shaped as goblet
Protects and lubricates many internal body surfaces
Kartengeer’s syndrome
Immotile cilia syndrome
Inherited disease
Frequent respiratory infections
Infertility
Keratinized simple squamous epithelium
Epidermis
Contains protective protein keratin
Waterproof
Surface cells are dead and full of keratin