Lecture 8 Flashcards

1
Q

3 Main types of Hormones

A
  1. Peptide/Protein
  2. Steroid
  3. Amine
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2
Q

2 classifications of hormones

A
  1. Hydrophilic
  2. Hydrophobic
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3
Q

Hydrophilic Hormones

A
  • Water soluble, plasma soluble
  • Lipid insoluble (lipophobic)
  • Unable to cross through plasma membranes
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4
Q

Hydrophobic hormones

A
  • Water insoluble, plasma insoluble
  • Lipid soluble (lipophilic)
  • Rapidly crosses the plasma membrane
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5
Q

What are peptide/protein hormones derived from?

A

3 or more amino acids

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6
Q

What are steroid hormones derived from?

A

cholesterol

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7
Q

What are amine hormones derived from?

A

single amino acids

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8
Q

Melatonin

A
  • Secreted at night (sleep)
  • Made in the pineal gland (also gi tract, leukocytes and other brain regions)
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9
Q

Amine Hormones

A

Synthesized only from tryptophan or tyrosine

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10
Q

Tryptophan derivative

A

melatonin (behaves like peptides or steroids)

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11
Q

Tyrosine derivatives

A
  • catecholamines (behave like peptides)
  • Thyroid hormones (behave like steroids)
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12
Q

Control of hormone release

A

endocrine cells directly sense stimuli, then secrete the hormone

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13
Q

Synergistic Effects

A
  • Multiple hormones act together for greater effect
  • Synergism between FSH and testosterone on sperm production
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14
Q

Permissive Effects

A
  • One hormone enhances the target organ’s response to a second later hormone
  • Estrogen prepares the uterus for action of progesterone
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15
Q

Antagonistic Effects

A
  • One hormone opposes the action of another
  • Insulin lowers blood glucose and glucagon raises it
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16
Q

Where do protein hormones act?

A

react with receptors on the surface of the cell, and the sequence of events that results in hormone action is relatively rapid

17
Q

Where do steroid hormones act?

A

The complex is broken down inside the lysosome, and free steroid hormone diffuses into the cell, where it subsequently exerts its action at the genomic level or undergoes metabolism