Lecture 12 Flashcards
Adrenal medulla
modified sympathetic ganglia (each secretory cell is a neuron without an axon)
Adrenal cortex
- the body’s steroid factory
the outer region and largest part of the adrenal gland
Catecholamine
a hormone produced by the adrenal glands located above the kidneys
- Increases heart rate, blood pressure, breathing rate, muscle strength and mental alertness
3 Main types of catecholamines
- Dopamine
- Norepinephrine
- Epinephrine
Androgens
are sex hormones
ACTH
Adrenocorticotropic hormone- produced by the anterior pituitary & increases androgen production
What regulates catecholamine release from the adrenal medulla
The main hormone is epinephrine because it is secreted in sufficient quantity to exert effects
Catecholamine release is stimulated by….
activation of the sympathetic nervous system (“fight or flight” response)
Glucocorticoid
steroid hormones produced from the cortex of adrenal glands and fight inflammation and work with your immune system to treat wide range of health problems
Cortisol
is a long term stress hormone and steroid hormone (and the main glucocorticoid) which increases glucose levels in the bloodstream and increases the availability of substances in the body that repair tissue. Continuous secretion, diurnal rhythm (plays a critical role in the circadian rhythm)
Analongs
similarity of function and superficial resemblance of structures that have different origins.
For example, the wings of a fly, a moth, and a bird are analogous because they developed independently as adaptations to a common function—flying
4 Cortisol Essential functions
- Promotes gluconeogenesis
- Causes breakdown of skeletal muscle proteins
- Enhances lipolysis
- Suppresses the immune system
Adrenal Hormone disorders
- Addison’s disease
- Cushing’s syndrome
Addison’s disease
adrenal insufficiency
- hyposecretion of adrenal steroid hormones
- hypotension & hypoglycemia
Cushing’s syndrome
cortisol excess
- hyperglycemia