Lecture 6 Flashcards

1
Q

The Blood Brain Barrier Is a 2 fold entity Between…

A
  1. Blood Vessels & Interstitial Fluid
  2. Blood Vessels & CSF
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2
Q

3 factors of Brain Encasing

A
  1. Skull
  2. Meninges
  3. Reticular Formation
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3
Q

Blood-Brain Barrier

A

The endothelial lining of the blood vesicles contain mostly large gaps-

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4
Q

Fenestrations

A

pores in which molecules can pass

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5
Q

Important features of the endothelial cells in the brain

A

it contains no pores (this is what makes up the BBB, everything has to be transported)

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6
Q

Meninges

A

Three layers of membranes known as meninges protect the brain and spinal cord.

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7
Q

3 layers of the meninges (outside-inside)

A
  1. Dura Mater
  2. Arachnoid membrane
  3. Pia mater
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8
Q

Ventricles

A

cavities deep inside the brain which are filled with CSF (which is the bathing medium of brain- highly regulated ionic content and few macromolecules)

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9
Q

Cerebral spinal fluid is produced by the ________

A

choroid plexus (and lines the ventricles)

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10
Q

Arachnoid Villi

A

an out pouching of the arachnoid tissue

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11
Q

Choroid Plexus

A

produces most CSF but not all- about 550 ml/day (some CSF is produced in the capillaries inside the brain)

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12
Q

CSF (cerebral-spinal fluid)

A
  • Fills the ventricles and the subarachnoid space
    • Has same osmolarity and [Na+] as blood
    • LOW [K+], [Ca2+] and [Mg2+]
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13
Q

Astrocytes

A

provide a bridge between neurons and blood vessels

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14
Q

A Lumbar Puncture

A

(spinal tap) is a diagnostic, therapeutic procedure to collect a sample of CSF for analysis

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15
Q

2 functions of astrocytes

A

1) Remove neurotransmitters
2) Provide energy substrates

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