Lecture 7: Exocrine Glands Flashcards
Parenchyma
glandular epithelium constituting the secretory cells of the gland
Exocrine glands can be found in?
integument
digestive system
respiratory system
reproductive system
Exocrine glands in the integument include?
lacrimal glands- tear production
sebaceous glands- produce oily sebum- zits
sweat glands- sweat production
mammary glands- milk production
Exocrine glands of the digestive system include?
salivary glands
mucosa of GI tract, including gastric glands
pancreas
Exocrine glands of the respiratory system include?
nasal mucosa
airways
Exocrine glands in the reproductive system include?
mucous glands
male accessory sex organs (prostate, seminal vesicles)
Exocrine gland classification is done on the basis of?
The structure of the duct system
- simple- duct unbranched, small gland in organ
- compound- hierarchy of branching; ductwork ramified; large gland; lobed/lobulated
Shape of the secretory portion
- tubular- test tube like
- acinar(alveolar)- bags with small/large lumen
- tubuloacinar
Exocrine gland secretions include
serous
mucous
seromucous
Serrous secretions
- secretion is thin and watery, rich in protein (usually enzymes)
- cell nucleus is round, central (can also be located basally)
- eosinophilic with H&E
Mucous secretions
secretion is viscous and slimy
cell nuclues is basally-located and flat
white/clear secretion with H&E stain
Seromucous secretions
- Acini secrete seromucous which have both serous and mucous components
- serous demilunes surround the acini and secrete into the space between the mucous cell
Mechanism of secretion include
Holocrine
Merocrine
Apocrine
Holocrine mechanisms of secretion
- the secretory product accumulate within the maturing cells
- programmed cell death
- product and apoptotic cell fragments discharged into the lumen of the duct
Where are holocrine secretions?
sebaceous glands of the skin
Melocrine mechanism of secretion?
Merocrine cells can be seen in?
salivary glands
pancrease
eccrine sweat glands
Aprocrine cells can be seen in?
small portions of membrane pinch off to release the secretory product
-apocrine sweat gland, lactating mammary gland
Simple tubular
straight, unbranched
like a test tube
found in the instestine
Simple branched tubular
branched tubular secretory regions
single, unbranched duct
found mainly in the stomach
Simple colied tubular
- single tube that is tightly coiled in secretory region
- will see various profiles in one plane of section
- sweat glands
Simple branched acinar
- several acini secrete into single duct
- sebaceous gland
- holocrine mode of secretion
- sebum accumulates within secretory cells
- degeneration of cell discharges the sebum
Compound gland ductwork
intralobular ducts interlobular duct (inter)lobuar duct main duct
Intalobular ducts
- ductwork within a lobule; usually in the centre of the lobule
- types
- intercalated
- striated
Interlobular duct
ductwork between lobules; located within the interlobular CT
(inter)lobar ducts
ductwork located between lobes that drain each lobe
-will draine the lobe of that gland
Main duct
Formed by the convergence of lobar ducts